In this review, we outline the growing role that molecular dynamics simulation is able to play
as a design tool in drug delivery. We cover both the pharmaceutical and computational …

Traditional cancer therapy methods, especially those directed against specific intracellular
targets or signaling pathways, are not powerful enough to overcome tumor heterogeneity …

Background: Dental caries is the most prevalent bacterial biofilm-induced disease. Current
clinical prevention and treatment agents often suffer from adverse effects on oral microbiota …

The security issue of human health is faced with dispiriting threats from multidrug-resistant
bacteria infections induced by the abuse and misuse of antibiotics. Over decades, the …

Peptidic biomaterials represent a particularly exciting topic in regenerative medicine.
Peptidic scaffolds can be specifically designed for biomimetic customization for targeted …

Nanotechnology has become a powerful tool to potentially translate nanomedicine from
bench to bedside. Nanotherapeutics are nanoparticles (NPs) loaded with drugs and …

Antimicrobial peptides (AMPs) are potent antibiotics of the innate immune system that have
been extensively investigated as a potential solution to the global problem of infectious …

The tumor immune microenvironment (TIME) is one of the significant hallmarks of cancer
and has the important role of largely determining the malignancy level of tumors. As an …

In this work, we report a drug delivery system based on the pH-responsive self-assembly
and-disassembly behaviors of peptides. Here, a systematically designed histidine-rich …

Following considerable research efforts on antimicrobial effects by cationic and amphiphilic
peptides during the last couple of decades, increasing focus has recently been placed on …