SNP genotyping: technologies and biomedical applications

S Kim, A Misra - Annu. Rev. Biomed. Eng., 2007 - annualreviews.org
Single nucleotide polymorphisms (SNPs) are the most frequently occurring genetic variation
in the human genome, with the total number of SNPs reported in public SNP databases …

Nucleic acid detection based on the use of microbeads: a review

S Rödiger, C Liebsch, C Schmidt, W Lehmann… - Microchimica Acta, 2014 - Springer
Microbead-based technologies represent elegant and versatile approaches for highly
parallelized quantitative multiparameter assays. They also form the basis of various …

Rolling circle amplification combined with gold nanoparticle aggregates for highly sensitive identification of single-nucleotide polymorphisms

J Li, T Deng, X Chu, R Yang, J Jiang, G Shen… - Analytical …, 2010 - ACS Publications
A highly sensitive and specific colorimetry-based rolling circle amplification (RCA) assay
method for single-nucleotide polymorphism genotyping has been developed. A circular …

Application of nanomaterials in the bioanalytical detection of disease-related genes

X Zhu, J Li, H He, M Huang, X Zhang… - Biosensors and …, 2015 - Elsevier
In the diagnosis of genetic diseases and disorders, nanomaterials-based gene detection
systems have significant advantages over conventional diagnostic systems in terms of …

Novel biosensing methodologies for improving the detection of single nucleotide polymorphism

K Chang, S Deng, M Chen - Biosensors and Bioelectronics, 2015 - Elsevier
The growing volume of sequence data confirm more and more candidate single nucleotide
polymorphisms (SNPs), which are believed to reveal the genetic basis of individual …

One-shot high-resolution melting curve analysis for KRAS point-mutation discrimination on a digital microfluidics platform

M Li, L Wan, MK Law, L Meng, Y Jia, PI Mak… - Lab on a Chip, 2022 - pubs.rsc.org
Single-nucleotide polymorphism (SNP) plays a critical role in personalized medicine,
forensics, pharmacogenetics, and disease diagnostics. Among different existing SNP …

Combination of DNA ligase reaction and gold nanoparticle-quenched fluorescent oligonucleotides: a simple and efficient approach for fluorescent assaying of single …

H Wang, J Li, Y Wang, J Jin, R Yang, K Wang… - Analytical …, 2010 - ACS Publications
A new fluorescent sensing approach for detection of single-nucleotide polymorphisms
(SNPs) is proposed based on the ligase reaction and gold nanoparticle (AuNPs)-quenched …

[HTML][HTML] Ultrasensitive detection of DNA by PNA and nanoparticle-enhanced surface plasmon resonance imaging (468 views)

R D'agata, R Corradini, G Grasso, R Marchelli… - … (ISSN: 1439-4227, 1439 …, 2008 - ibb.cnr.it
Ultrasensitive detection of DNA by PNA and nanoparticle-enhanced surface plasmon resonance
imaging Institute About us Documents News Organization chart Locations Staff Contact us …

Sub-7-second genotyping of single-nucleotide polymorphism by high-resolution melting curve analysis on a thermal digital microfluidic device

T Chen, Y Jia, C Dong, J Gao, PI Mak, RP Martins - Lab on a Chip, 2016 - pubs.rsc.org
We developed a thermal digital microfluidic (T-DMF) device enabling ultrafast DNA melting
curve analysis (MCA). Within 7 seconds, the T-DMF device succeeded in differentiating a …

[图书][B] In situ molecular pathology and co-expression analyses

GJ Nuovo - 2020 - books.google.com
Major advancements in the field of in situ molecular pathology have occurred since
publication of the first edition. In Situ Molecular Pathology and Co-expression Analyses …