Betalactam (BL) antibiotics are the drugs most frequently involved in IgE‐mediated
reactions. The culprit BL varies according to consumption patterns, with amoxicillin (AX) …

Introduction: Betalactams are the most widely used drugs against infections and the primary
cause of antibiotic hypersensitivity reactions. Reaction patterns for different betalactams …

Polyamidoamine (PAMAM) dendrimers, a class of polymeric nanoparticles (NPs) with highly
controllable sizes and surface chemistry, are promising candidates for many biomedical …

The arginine–glycine–aspartic acid (RGD) peptide sequence is known to specifically interact
with integrins, which are chief receptors participating at various stages of cancer disease …

β-lactam antibiotics (BLs) are the drugs most frequently involved in drug hypersensitivity
reactions. However, current in vitro diagnostic tests have limited sensitivity, partly due to a …

The optimal recognition of penicillin determinants, including amoxicillin (AX), by specific IgE
antibodies is widely believed to require covalent binding to a carrier molecule. The nature of …

Dendrimeric Antigens (DeAns) consist of dendrimers decorated with multiple units of drug
antigenic determinants. These conjugates have been shown to be a powerful tool for …

In vitro cell activation through specific IgE bound to high-affinity receptors on the basophil
surface is a widely used strategy for the evaluation of IgE-mediated immediate …

Nanotechnology is science, engineering and technology conducted at the nanoscale, which
is about 1–100 nm. It has led to the development of nanomaterials, which behave very …

Herein, we present an easy and efficient synthesis of amino terminal dendrons, combining
protection/deprotection reactions with copper-catalyzed azide alkyne cycloaddition in a …