A well-functioning immune system is vital for a healthy body. Inadequate and excessive
immune responses underlie diverse pathologies such as serious infections, metastatic …

Inflammation is the initial response of the immune system to potentially harmful stimuli (eg,
injury, stress, and infections). The process involves activation of macrophages and …

Since the WHO declared COVID-19 a pandemic, a great effort has been made to understand
this serious disease. Thousands of studies are being devoted to understanding its …

Fever is a cardinal response to infection that has been conserved in warm-blooded and cold-
blooded vertebrates for more than 600 million years of evolution. The fever response is …

The past 15 years have seen enormous advances in our understanding of the receptor and
signalling systems that allow dendritic cells (DCs) to respond to pathogens or other danger …

In this FlyBook chapter, we present a survey of the current literature on the development of
the hematopoietic system in Drosophila. The Drosophila blood system consists entirely of …

COVID-19 is a zoonotic disease with devastating economic and public health impacts
globally. Being a novel disease, current research is focused on a clearer understanding of …

Pathogenic bacteria taken up into the macrophage phagosome are the target of many anti-
microbial mechanisms. Although mitochondria-derived antimicrobial effectors like reactive …

To thrive and to fulfill their functions, cells need to maintain proteome homeostasis even in
the face of adverse environmental conditions or radical restructuring of the proteome during …

Pro-inflammatory stress is inherent in any cells that are subject to damage or threat of
damage. It is defined by a number of universal components, including oxidative stress …