Parkinson's disease: Mechanisms, translational models and management strategies
C Raza, R Anjum - Life sciences, 2019 - Elsevier
Parkinson's disease is a progressive neurodegenerative disorder. The classical motor
symptoms include resting tremors, bradykinesia, rigidity and postural instability and are …
symptoms include resting tremors, bradykinesia, rigidity and postural instability and are …
[HTML][HTML] Parkinson's disease: biomarkers, treatment, and risk factors
FN Emamzadeh, A Surguchov - Frontiers in neuroscience, 2018 - frontiersin.org
Parkinson's disease (PD) is a progressive neurodegenerative disorder caused mainly by
lack of dopamine in the brain. Dopamine is a neurotransmitter involved in movement …
lack of dopamine in the brain. Dopamine is a neurotransmitter involved in movement …
Towards fog-driven IoT eHealth: Promises and challenges of IoT in medicine and healthcare
Abstract Internet of Things (IoT) offers a seamless platform to connect people and objects to
one another for enriching and making our lives easier. This vision carries us from compute …
one another for enriching and making our lives easier. This vision carries us from compute …
[HTML][HTML] Current understanding of the molecular mechanisms in Parkinson's disease: Targets for potential treatments
P Maiti, J Manna, GL Dunbar - Translational neurodegeneration, 2017 - Springer
Gradual degeneration and loss of dopaminergic neurons in the substantia nigra, pars
compacta and subsequent reduction of dopamine levels in striatum are associated with …
compacta and subsequent reduction of dopamine levels in striatum are associated with …
[HTML][HTML] Initiation and propagation of α-synuclein aggregation in the nervous system
BA Hijaz, LA Volpicelli-Daley - Molecular neurodegeneration, 2020 - Springer
The two main pathological hallmarks of Parkinson's disease are loss of dopamine neurons
in the substantia nigra pars compacta and proteinaceous amyloid fibrils composed mostly of …
in the substantia nigra pars compacta and proteinaceous amyloid fibrils composed mostly of …
Quantitative susceptibility mapping (QSM): decoding MRI data for a tissue magnetic biomarker
In MRI, the main magnetic field polarizes the electron cloud of a molecule, generating a
chemical shift for observer protons within the molecule and a magnetic susceptibility …
chemical shift for observer protons within the molecule and a magnetic susceptibility …
[HTML][HTML] Closed-loop stimulation of temporal cortex rescues functional networks and improves memory
Memory failures are frustrating and often the result of ineffective encoding. One approach to
improving memory outcomes is through direct modulation of brain activity with electrical …
improving memory outcomes is through direct modulation of brain activity with electrical …
[HTML][HTML] Parkinson's disease: A review
DM Radhakrishnan, V Goyal - Neurology India, 2018 - journals.lww.com
Parkinson's disease is a common movement disorder seen in neurological practice, but the
diagnosis and management is challenging. The diagnosis is clinical and sometimes difficult …
diagnosis and management is challenging. The diagnosis is clinical and sometimes difficult …
Parkinson disease
W Poewe, K Seppi, CM Tanner, GM Halliday… - Nature reviews Disease …, 2017 - nature.com
Parkinson disease is the second-most common neurodegenerative disorder that affects 2–
3% of the population≥ 65 years of age. Neuronal loss in the substantia nigra, which causes …
3% of the population≥ 65 years of age. Neuronal loss in the substantia nigra, which causes …
[HTML][HTML] Deep brain stimulation programming for movement disorders: current concepts and evidence-based strategies
Deep brain stimulation (DBS) has become the treatment of choice for advanced stages of
Parkinson's disease, medically intractable essential tremor, and complicated segmental and …
Parkinson's disease, medically intractable essential tremor, and complicated segmental and …