Simple Summary Cancer, a major public health issue worldwide, is the second most
common cause of death. Initiatives such as the Human Genome Project (HGP) and Human …

The protein ISG15 encoded by interferon-stimulated gene (ISG) 15 is the first identified
member of the ubiquitin-like protein family and exists in the form of monomers and …

In-depth LC–MS-based proteomic profiling of limited biological and clinical samples, such
as rare cells or tissue sections from laser capture microdissection or microneedle biopsies …

Fructus Psoraleae (FP), one of the significant traditional Chinese medicines, has been
reported to cause hepatotoxicity. However, the mechanism remains undetermined and the …

Lymph node (LN) fine needle aspiration (LN FNA) represents a powerful technique for
minimally invasive sampling of human LNs in vivo and has been used effectively to directly …

Introduction Despite advancements in diagnostic methods, the classification of
indeterminate thyroid nodules still poses diagnostic challenges not only in pre-surgical …

The incidence of thyroid cancer (TC) has been increasing over the last 50 years worldwide.
A higher rate of overdiagnosis in indolent thyroid lesions has resulted in unnecessary …

Background Lymph node metastasis (LNM) in papillary thyroid microcarcinoma (PTMC) is
associated with an increased risk of recurrence and poor prognosis. Sex has been regarded …

Exosomes are a type of extracellular vehicle, formed by budding cell membranes, containing
proteins, DNA, and RNA. Concentrated cargoes from parent cells are enveloped in …

Abstract Background Metastatic prostate cancer (PCa) is a lethal tumor. However, the
molecular mechanisms underlying PCa progression have not been fully elucidated …