The therapeutic limitations such as insufficient efficacy, drug resistance, metastasis, and
undesirable side effects are frequently caused by the long duration monotherapy based on …

Cancer remains a significant risk to human health. Nanomedicine is a new multidisciplinary
field that is garnering a lot of interest and investigation. Nanomedicine shows great potential …

Since its license in 1978, cisplatin has proved to be one of the most successful
chemotherapeutic agents in the world. However, two acute challenges facing cisplatin …

Cancer is the main cause of morbidity and mortality worldwide, excluding infectious disease.
Because of their lack of specificity in chemotherapy agents are used for cancer treatment …

Natural compounds have significant anticancer pharmacological activities, but often suffer
from low bioavailability and selectivity that limit therapeutic use. The present work critically …

As an essential trace element, selenium participates in numerous important life processes
and plays a significant role for human beings. Owning to its unique physical, chemical and …

Platinum drugs are commonly used in cancer therapy, but their therapeutic outcomes have
been significantly compromised by the drug resistance of cancer cells. To this end, intensive …

Background Ovarian cancer is a common malignancy in the female reproductive system with
a high mortality rate. The most important reason is multidrug resistance (MDR) of cancer …

Chemoradiotherapy is a widely used treatment for patients with malignancies such as
hepatocellular carcinoma (HCC). However, it remains challenging to realize safe and …

Nanoparticles (NPs) have been increasingly studied for radiosensitization. The principle of
NPs radio-enhancement is to use high-atomic number NPs (eg gold, hafnium, bismuth and …