High‐throughput metabolomics by 1D NMR

A Vignoli, V Ghini, G Meoni, C Licari… - Angewandte Chemie …, 2019 - Wiley Online Library
Metabolomics deals with the whole ensemble of metabolites (the metabolome). As one of
the‐omic sciences, it relates to biology, physiology, pathology and medicine; but metabolites …

[HTML][HTML] Applications of machine learning in metabolomics: Disease modeling and classification

A Galal, M Talal, A Moustafa - Frontiers in genetics, 2022 - frontiersin.org
Metabolomics research has recently gained popularity because it enables the study of
biological traits at the biochemical level and, as a result, can directly reveal what occurs in a …

Global metabolic profiling procedures for urine using UPLC–MS

EJ Want, ID Wilson, H Gika, G Theodoridis, RS Plumb… - Nature protocols, 2010 - nature.com
The production of'global'metabolite profiles involves measuring low molecular-weight
metabolites (< 1 kDa) in complex biofluids/tissues to study perturbations in response to …

Chemometrics in metabolomics—a review in human disease diagnosis

R Madsen, T Lundstedt, J Trygg - Analytica chimica acta, 2010 - Elsevier
Metabolomics is a post genomic research field concerned with developing methods for
analysis of low molecular weight compounds in biological systems, such as cells, organs or …

Role of the gut microbiota in defining human health

KE Fujimura, NA Slusher, MD Cabana… - Expert review of anti …, 2010 - Taylor & Francis
The human superorganism is a conglomerate of mammalian and microbial cells, with the
latter estimated to outnumber the former by ten to one and the microbial genetic repertoire …

[HTML][HTML] Diagnosis and management of secondary causes of steatohepatitis

R Liebe, I Esposito, HH Bock, S Vom Dahl, J Stindt… - Journal of …, 2021 - Elsevier
The term non-alcoholic liver disease (NAFLD) was originally coined to describe hepatic fat
deposition as part of the metabolic syndrome. However, a variety of rare hereditary liver and …

NMR-based metabolomics in human disease diagnosis: applications, limitations, and recommendations

AHM Emwas, RM Salek, JL Griffin, J Merzaban - Metabolomics, 2013 - Springer
Metabolomics is a dynamic and emerging research field, similar to proteomics,
transcriptomics and genomics in affording global understanding of biological systems. It is …

[HTML][HTML] Visualising associations between paired 'omics' data sets

I González, KAL Cao, MJ Davis, S Déjean - BioData mining, 2012 - Springer
Background Each omics platform is now able to generate a large amount of data. Genomics,
proteomics, metabolomics, interactomics are compiled at an ever increasing pace and now …

[HTML][HTML] Standardizing the experimental conditions for using urine in NMR-based metabolomic studies with a particular focus on diagnostic studies: a review

AH Emwas, C Luchinat, P Turano, L Tenori, R Roy… - Metabolomics, 2015 - Springer
The metabolic composition of human biofluids can provide important diagnostic and
prognostic information. Among the biofluids most commonly analyzed in metabolomic …

Standard operating procedures for pre-analytical handling of blood and urine for metabolomic studies and biobanks

P Bernini, I Bertini, C Luchinat, P Nincheri… - Journal of biomolecular …, 2011 - Springer
Abstract 1 H NMR metabolic profiling of urine, serum and plasma has been used to monitor
the impact of the pre-analytical steps on the sample quality and stability in order to propose …