The suprachiasmatic nucleus (SCN) of the hypothalamus is remarkable. Despite numbering
only about 10,000 neurons on each side of the third ventricle, the SCN is our principal …

It has been 50 years since the suprachiasmatic nucleus (SCN) was first identified as the
central circadian clock and 25 years since the last overview of developments in the field was …

The hypothalamus is a central regulator of many innate behaviors essential for survival, but
the molecular mechanisms controlling hypothalamic patterning and cell fate specification …

The hypothalamic suprachiasmatic (SCN) clock contains several neurochemically defined
cell groups that contribute to the genesis of circadian rhythms. Using cell-specific and …

Large-scale genomic and transcriptomic initiatives offer unprecedented insight into complex
traits, but clinical translation remains limited by variant-level associations without biological …

The light environment greatly impacts human alertness, mood, and cognition by both acute
regulation of physiology and indirect alignment of circadian rhythms. These processes …

The neuroendocrine hypothalamus is the central regulator of vital physiological homeostasis
and behavior. However, the cellular and molecular properties of hypothalamic neural …

The suprachiasmatic nucleus (SCN) co-ordinates circadian behaviour and physiology in
mammals. Its cell-autonomous circadian oscillations pivot around a well characterised …

Abstract Study Objectives Aggregates of hyperphosphorylated tau protein are a hallmark of
Alzheimer's disease (AD) and other tauopathies. Sleep disturbances are common in AD …

With his bicentennial breeding history based on athletic performance, the Thoroughbred
horse can be considered the equine sport breed. Although genomic and transcriptomic tools …