Drug delivery to the posterior segment of the eye: biopharmaceutic and pharmacokinetic considerations

R Varela-Fernández, V Díaz-Tomé… - Pharmaceutics, 2020 - mdpi.com
The treatment of the posterior-segment ocular diseases, such as age-related eye diseases
(AMD) or diabetic retinopathy (DR), present a challenge for ophthalmologists due to the …

Infectious uveitis in horses and new insights in its leptospiral biofilm-related pathogenesis

B Wollanke, H Gerhards, K Ackermann - Microorganisms, 2022 - mdpi.com
Uveitis is a sight-threatening eye disease in equids known worldwide that leads to
considerable pain and suffering. By far the most common type of uveitis in Germany and …

The Infectious Uveitis Treatment Algorithm Network (TITAN) Report 2—global current practice patterns for the management of Cytomegalovirus anterior uveitis

ZX Thng, I Putera, I Testi, K Chan, M Westcott, SP Chee… - Eye, 2024 - nature.com
Aims To present current practice patterns in the diagnosis and management of
Cytomegalovirus anterior uveitis (CMV AU) by uveitis experts worldwide. Methods A two …

From Bedside to Diagnosis: The Role of Ocular Fundus in Systemic Infections

G Visioli, M Zeppieri, V Iannucci, P Manni… - Journal of Clinical …, 2023 - mdpi.com
In this comprehensive review, we delve into the significance of the ocular fundus
examination in diagnosing and managing systemic infections at the bedside. While the …

The impact of aqueous humor polymerase chain reaction and serological test results for establishing infectious uveitis diagnosis: An Indonesian experience

I Putera, RLD Nora, N Utami, A Karuniawati, A Yasmon… - Heliyon, 2022 - cell.com
Objective To assess the clinical value of aqueous humor real-time polymerase chain
reaction (RT-PCR) and serological antibody tests among uveitis patients in Indonesian …

An All-in-One Highly Multiplexed Diagnostic Assay for Rapid, Sensitive, and Comprehensive Detection of Intraocular Pathogens

PJM Bispo, N Belanger, A Li, R Liu, G Susarla… - American journal of …, 2023 - Elsevier
PURPOSE Intraocular infections are sight-threatening conditions that can lead to vision loss.
Rapid identification of the etiologies plays a key role in early initiation of effective therapy to …

Exogenous Fungal Endophthalmitis: Clues to Aspergillus Aetiology with a Pharmacological Perspective

T Lupia, S Corcione, AM Fea, M Reibaldi, M Fallico… - Microorganisms, 2020 - mdpi.com
Exogenous fungal endophthalmitis (EXFE) represents a rare complication after penetrating
ocular trauma of previously unresolved keratitis or iatrogenic infections, following intraocular …

Recent advances in the management of non-infectious posterior uveitis

RB Singh, S Sinha, C Saini, E Elbasiony… - International …, 2020 - Springer
Purpose To review the current regimens and novel therapeutic modalities in various stages
of research and development for the management of non-infectious posterior uveitis (NIPU) …

Clinical Insights: Antimicrobial Therapy for Infectious Uveitis

E Leong, C Cifuentes-González, J Hu YW… - Ocular Immunology …, 2024 - Taylor & Francis
Infectious uveitis is a major global cause of vision impairment. Despite the eye's immune
privilege, afforded by the blood-ocular barrier that restricts microbial entry, several …

[HTML][HTML] Synthetic lincosamides iboxamycin and cresomycin are active against ocular multidrug-resistant methicillin-resistant Staphylococcus aureus carrying erm …

C André, KJY Wu, AG Myers, PJM Bispo - Journal of Global Antimicrobial …, 2024 - Elsevier
Objective Antimicrobial resistance is a global pandemic that poses a major threat to vision
health as ocular bacteria, especially methicillin-resistant Staphylococcus aureus (MRSA) …