Applying the Bradford Hill criteria for causation to repetitive head impacts and chronic traumatic encephalopathy

CJ Nowinski, SC Bureau, ME Buckland… - Frontiers in …, 2022 - frontiersin.org
Chronic traumatic encephalopathy (CTE) is a neurodegenerative disease associated with a
history of repetitive head impacts (RHI). CTE was described in boxers as early as the 1920s …

Examining later-in-life health risks associated with sport-related concussion and repetitive head impacts: a systematic review of case-control and cohort studies

GL Iverson, RJ Castellani, JD Cassidy… - British journal of sports …, 2023 - bjsm.bmj.com
Objective Concern exists about possible problems with later-in-life brain health, such as
cognitive impairment, mental health problems and neurological diseases, in former athletes …

Leveraging football accelerometer data to quantify associations between repetitive head impacts and chronic traumatic encephalopathy in males

DH Daneshvar, ES Nair, ZH Baucom, A Rasch… - Nature …, 2023 - nature.com
Chronic traumatic encephalopathy (CTE) is a neurodegenerative tauopathy associated with
repetitive head impacts (RHI), but the components of RHI exposure underlying this …

Clinicopathological evaluation of chronic traumatic encephalopathy in players of American football

J Mez, DH Daneshvar, PT Kiernan… - Jama, 2017 - jamanetwork.com
Importance Players of American football may be at increased risk of long-term neurological
conditions, particularly chronic traumatic encephalopathy (CTE). Objective To determine the …

A systematic review of potential long-term effects of sport-related concussion

G Manley, AJ Gardner, KJ Schneider… - British journal of sports …, 2017 - bjsm.bmj.com
Objective Systematic review of possible long-term effects of sports-related concussion in
retired athletes. Data sources Ten electronic databases. Study selection Original research; …

Traumatic brain injuries

K Blennow, DL Brody, PM Kochanek, H Levin… - Nature reviews Disease …, 2016 - nature.com
Traumatic brain injuries (TBIs) are clinically grouped by severity: mild, moderate and severe.
Mild TBI (the least severe form) is synonymous with concussion and is typically caused by …

Association of mild traumatic brain injury with and without loss of consciousness with dementia in US military veterans

DE Barnes, AL Byers, RC Gardner, KH Seal… - JAMA …, 2018 - jamanetwork.com
Importance Traumatic brain injury (TBI) is common in both veteran and civilian populations.
Prior studies have linked moderate and severe TBI with increased dementia risk, but the …

Tau positron-emission tomography in former national football league players

RA Stern, CH Adler, K Chen, M Navitsky… - New England journal …, 2019 - Mass Medical Soc
Background Chronic traumatic encephalopathy (CTE) is a neurodegenerative disease that
has been associated with a history of repetitive head impacts. The neuropathological …

Sport-related concussion and mental health outcomes in elite athletes: a systematic review

SM Rice, AG Parker, S Rosenbaum, A Bailey… - Sports medicine, 2018 - Springer
Background Elite athletes can experience a diverse range of symptoms following post-
concussive injury. The impact of sport-related concussion on specific mental health …

Concussion, microvascular injury, and early tauopathy in young athletes after impact head injury and an impact concussion mouse model

CA Tagge, AM Fisher, OV Minaeva… - Brain, 2018 - academic.oup.com
The mechanisms underpinning concussion, traumatic brain injury, and chronic traumatic
encephalopathy, and the relationships between these disorders, are poorly understood. We …