The Allen Ancient DNA Resource (AADR) a curated compendium of ancient human genomes

S Mallick, A Micco, M Mah, H Ringbauer, I Lazaridis… - Scientific Data, 2024 - nature.com
More than two hundred papers have reported genome-wide data from ancient humans.
While the raw data for the vast majority are fully publicly available testifying to the …

The 2022 Nucleic Acids Research database issue and the online molecular biology database collection

DJ Rigden, XM Fernández - Nucleic acids research, 2022 - academic.oup.com
Abstract The 2022 Nucleic Acids Research Database Issue contains 185 papers, including
87 papers reporting on new databases and 85 updates from resources previously published …

SARS-CoV-2 resistance to monoclonal antibodies and small-molecule drugs

S Iketani, DD Ho - Cell Chemical Biology, 2024 - cell.com
Over four years have passed since the beginning of the COVID-19 pandemic. The scientific
response has been rapid and effective, with many therapeutic monoclonal antibodies and …

[HTML][HTML] A comprehensive overview of microbiome data in the light of machine learning applications: categorization, accessibility, and future directions

B Kumar, E Lorusso, B Fosso, G Pesole - Frontiers in Microbiology, 2024 - frontiersin.org
Metagenomics, Metabolomics, and Metaproteomics have significantly advanced our
knowledge of microbial communities by providing culture-independent insights into their …

Predicting the role of the human gut microbiome in type 1 diabetes using machine-learning methods

XW Liu, HL Li, CY Ma, TY Shi, TY Wang… - Briefings in …, 2024 - academic.oup.com
Gut microbes is a crucial factor in the pathogenesis of type 1 diabetes (T1D). However, it is
still unclear which gut microbiota are the key factors affecting T1D and their influence on the …

Bioprospecting and marine 'omics': surfing the deep blue sea for novel bioactive proteins and peptides

I Moutinho Cabral, C Gonçalves, AR Grosso… - Frontiers in Marine …, 2024 - frontiersin.org
The vast biological and biochemical diversity of the global ocean is the driver behind marine
bioprospecting for novel bioproducts. As Marine Biotechnology is gaining momentum as one …

[HTML][HTML] Bioinformatics Goes Viral: I. Databases, Phylogenetics and Phylodynamics Tools for Boosting Virus Research

F Vello, F Filippini, I Righetto - Viruses, 2024 - mdpi.com
Computer-aided analysis of proteins or nucleic acids seems like a matter of course
nowadays; however, the history of Bioinformatics and Computational Biology is quite recent …

Sequencing technologies and hardware-accelerated parallel computing transform computational genomics research

M Olbrich, L Bartels, I Wohlers - Frontiers in Bioinformatics, 2024 - frontiersin.org
High-throughput sequencing and hardware-accelerated computing have both developed
tremendously within the last decade. In genomics, progress is fueled by new technologies …

IPEV: identification of prokaryotic and eukaryotic virus-derived sequences in virome using deep learning

H Yin, S Wu, J Tan, Q Guo, M Li, J Guo, Y Wang… - …, 2024 - academic.oup.com
Background The virome obtained through virus-like particle enrichment contains a mixture of
prokaryotic and eukaryotic virus-derived fragments. Accurate identification and classification …

Bioinformatics software development: Principles and future directions

XK Ma, Y Yu, T Huang, D Zhang, C Tian… - The Innovation …, 2024 - the-innovation.org
The bioinformatics software for analyzing biomedical data is essential for converting raw
data into meaningful biological insights. In this review, we outline the key stages and …