Long non-coding RNAs (lncRNAs) have become increasingly important in the past decade.
They are known to regulate gene expression and to interact with chromatin, proteins and …

Disseminated tumor cells often fall into a long term of dormant stage, characterized by
decreased proliferation but sustained survival, in distant organs before awakening for …

Long non-coding RNAs (lncRNAs) are a rapidly expanding field of research, with many new
transcripts identified each year. However, only a small subset of lncRNAs has been …

Prolonged pausing of the transcription machinery may lead to the formation of three-
stranded nucleic acid structures, called R-loops, typically resulting from the annealing of the …

The envelope of Gram-negative bacteria is a vital barrier that must balance protection and
nutrient uptake. Small RNAs are crucial regulators of the envelope composition and function …

In contrast to the catalytic subunit of telomerase, its RNA subunit (TR) is highly divergent in
size, sequence and biogenesis pathways across eukaryotes. Current views on TR evolution …

The SARS-CoV-2 virus is a recently-emerged zoonotic pathogen already well adapted to
transmission and replication in humans. Although the mutation rate is limited, recently …

The enormous sequence heterogeneity of telomerase RNA (TR) subunits has thus far
complicated their characterization in a wider phylogenetic range. Our recent finding that land …

The gram-positive human pathogen Clostridioides difficile has emerged as the leading
cause of antibiotic-associated diarrhea. However, little is known about the bacterium's …

Type I toxin–antitoxin systems (T1TAs) are bipartite bacterial loci encoding a growth-
inhibitory toxin and an antitoxin small RNA (sRNA). In many of these systems, the …