miRNAs can be found in serum and other body fluids and serve as biomarkers for disease.
More importantly, secreted miRNAs, especially those in extracellular vesicles (EVs) such as …

Background The prevalence and incidence of type 2 diabetes (T2D), representing> 90% of
all cases of diabetes, are increasing rapidly worldwide. Identification of individuals at high …

Over the last few years, the field of microribonucleic acid (miRNA) in cardiovascular biology
and disease has expanded at an incredible pace. miRNAs are themselves part of a larger …

Aims/hypothesis The aim was to identify potential microRNA (miRNA) biomarkers of type 2
diabetes. Methods Controlled studies were retrieved from PubMed to compare miRNA …

Objective Exosomes from obese adipose contain dysregulated microRNAs linked to insulin
signaling, as compared with lean controls, providing a direct connection between adiposity …

Purpose The unique circulating microRNAs (miRNAs) observed in patients with type 2
diabetes (T2D) are candidates as new biomarkers and therapeutic targets. In order to …

A major issue in aging research is how cellular phenomena affect aging at the systemic
level. Emerging evidence suggests that DNA damage response (DDR) signaling is a key …

Context: Diabetes is frequently diagnosed late, when the development of complications is
almost inevitable, decreasing the quality of life of patients. However, early detection of …

Context: Type 2 diabetes is a chronic disease characterized by inadequate β-cell response
to the progressive insulin resistance. MicroRNAs (miRNAs) are short, endogenous …

MicroRNAs (miRNAs) are small noncoding RNAs that modulate the cellular transcriptome at
the post-transcriptional level. miRNA plays important roles in different disease manifestation …