Shining new light on biological systems: luminescent transition metal complexes for bioimaging and biosensing applications

LCC Lee, KKW Lo - Chemical Reviews, 2024 - ACS Publications
Luminescence imaging is a powerful and versatile technique for investigating cell
physiology and pathology in living systems, making significant contributions to life science …

Underestimated potential of organometallic rhenium complexes as anticancer agents

A Leonidova, G Gasser - ACS chemical biology, 2014 - ACS Publications
In the recent years, organometallic compounds have become recognized as promising anti-
cancer drug candidates. While radioactive 186/188Re compounds are already used in …

Re (I) carbonyl complexes: Multimodal platforms for inorganic chemical biology

S Hostachy, C Policar, N Delsuc - Coordination Chemistry Reviews, 2017 - Elsevier
Bio-imaging, by enabling the visualization of biomolecules of interest, has proved to be
highly informative in the study of biological processes. Although fluorescence microscopy is …

Identification of novel potent and non-toxic anticancer, anti-angiogenic and antimetastatic rhenium complexes against colorectal carcinoma

J Delasoie, A Pavic, N Voutier, S Vojnovic… - European journal of …, 2020 - Elsevier
Combination therapy targeting both tumor growth and vascularization is considered to be a
cornerstone for colorectal carcinomas (CRC) treatment. However, the major obstacles of …

Trackable metallodrugs combining luminescent Re (I) and bioactive Au (I) fragments

A Luengo, V Fernandez-Moreira, I Marzo… - Inorganic …, 2017 - ACS Publications
Hetero-bimetallic and-trimetallic complexes were synthesized by the combination of different
metallic fragments, a luminescent Re (I) species, and a bioactive Au (I) derivative. A ditopic …

An introduction to organometallic complexes in fluorescence cell imaging: current applications and future prospects

FL Thorp-Greenwood - Organometallics, 2012 - ACS Publications
An introduction to the applications of organometallic complexes in fluorescence cell imaging
is presented. A brief summary of the chemical and photophysical properties which enable …

Enhanced cytotoxicity through conjugation of a “clickable” luminescent Re (I) complex to a cell-penetrating lipopeptide

A Leonidova, V Pierroz, LA Adams… - ACS medicinal …, 2014 - ACS Publications
Re (I) tricarbonyl polypyridine-based complexes are particularly attractive metal complexes
in the field of inorganic chemical biology due to their luminescent properties, ease of …

Rhenium (I) Complexes with Neutral Monodentate Coligands and Monoanionic 2-(1, 2, 4-Triazol-5-yl) pyridine-Based Chelators as Bidentate Luminophores with …

I Maisuls, TM Kirse, A Hepp, J Kösters… - Inorganic …, 2022 - ACS Publications
In this work, we describe the synthesis as well as structural, photophysical, and theoretical
investigation of a new coordination chemical concept involving rhenium (I) complexes …

Photophysical properties of rhenium (I) complexes and photosensitized generation of singlet oxygen

LD Ramos, HM da Cruz, KP Morelli Frin - Photochemical & Photobiological …, 2017 - Springer
Abstract fac-[Re (ampy)(CO) 3 (NN)]+ complexes (ampy= 2-aminomethylpyridine and NN=
1, 10-phenanthroline (phen), and 2, 2′-bipyridine (bpy)) were synthesized, purified and …

Neutral and Cationic Re (I) Complexes with Pnictogen-Based Coligands and Tunable Functionality: From Phosphorescence to Photoinduced CO Release

TM Kirse, I Maisuls, MV Cappellari… - Inorganic …, 2024 - ACS Publications
In this work, we have explored Re (I) complexes featuring triphenylpnictogen (PnPh 3, Pn=
P, As, or Sb)-based coligands and bidentate (neutral or monoanionic) luminophores derived …