The nature and neurobiology of fear and anxiety: State of the science and opportunities for accelerating discovery
Fear and anxiety play a central role in mammalian life, and there is considerable interest in
clarifying their nature, identifying their biological underpinnings, and determining their …
clarifying their nature, identifying their biological underpinnings, and determining their …
Incentive motivation:'wanting'roles of central amygdala circuitry
SM Warlow, KC Berridge - Behavioural brain research, 2021 - Elsevier
The central nucleus of amygdala (CeA) mediates positively-valenced reward motivation as
well as negatively-valenced fear. Optogenetic or neurochemical stimulation of CeA circuitry …
well as negatively-valenced fear. Optogenetic or neurochemical stimulation of CeA circuitry …
The central amygdala recruits mesocorticolimbic circuitry for pursuit of reward or pain
SM Warlow, EE Naffziger, KC Berridge - Nature communications, 2020 - nature.com
How do brain mechanisms create maladaptive attractions? Here intense maladaptive
attractions are created in laboratory rats by pairing optogenetic channelrhodopsin (ChR2) …
attractions are created in laboratory rats by pairing optogenetic channelrhodopsin (ChR2) …
A bidirectional corticoamygdala circuit for the encoding and retrieval of detailed reward memories
Adaptive reward-related decision making often requires accurate and detailed
representation of potential available rewards. Environmental reward-predictive stimuli can …
representation of potential available rewards. Environmental reward-predictive stimuli can …
A neuronal mechanism for motivational control of behavior
INTRODUCTION Acting to achieve goals underlies animals' behavioral flexibility and
depends on the ability to motivate specific behaviors. Formal studies of goal-directed …
depends on the ability to motivate specific behaviors. Formal studies of goal-directed …
Chemogenetic stimulation and silencing of the insula, amygdala, nucleus accumbens, and their connections differentially modulate alcohol drinking in rats
M Haaranen, A Schäfer, V Järvi… - Frontiers in behavioral …, 2020 - frontiersin.org
The anterior insular cortex is hypothesized to represent interoceptive effects of drug reward
in the service of goal-directed behavior. The insula is richly connected, but the insula …
in the service of goal-directed behavior. The insula is richly connected, but the insula …
[HTML][HTML] Aberrant orbitofrontal cortex reactivity to erotic cues in Compulsive Sexual Behavior Disorder
Abstract Background and aims Compulsive Sexual Behavior Disorder (CSBD) is
characterized by increased reactivity to erotic reward cues. Cue-encoded reward …
characterized by increased reactivity to erotic reward cues. Cue-encoded reward …
Endocannabinoid release at ventral hippocampal-amygdala synapses regulates stress-induced behavioral adaptation
The endocannabinoid (eCB) system is a key modulator of glutamate release within limbic
neurocircuitry and thus heavily modulates stress responsivity and adaptation. The ventral …
neurocircuitry and thus heavily modulates stress responsivity and adaptation. The ventral …
[HTML][HTML] Choose your path: Divergent basolateral amygdala efferents differentially mediate incentive motivation, flexibility and decision-making
To survive in a complex environment, individuals form associations between environmental
stimuli and rewards to organize and optimize reward seeking behaviors. The basolateral …
stimuli and rewards to organize and optimize reward seeking behaviors. The basolateral …
The basolateral amygdala and lateral hypothalamus bias learning towards motivationally significant events
Every day we are faced with a huge amount of new information. We can't learn about
everything, we have to select what to learn about. We have many systems that contribute to …
everything, we have to select what to learn about. We have many systems that contribute to …