Cerebral malaria induced by plasmodium falciparum: clinical features, pathogenesis, diagnosis, and treatment

X Song, W Wei, W Cheng, H Zhu, W Wang… - Frontiers in Cellular …, 2022 - frontiersin.org
Cerebral malaria (CM) caused by Plasmodium falciparum is a fatal neurological
complication of malaria, resulting in coma and death, and even survivors may suffer long …

Itaconate impairs immune control of Plasmodium by enhancing mtDNA-mediated PD-L1 expression in monocyte-derived dendritic cells

T Ramalho, PA Assis, O Ojelabi, L Tan, B Carvalho… - Cell Metabolism, 2024 - cell.com
Severe forms of malaria are associated with systemic inflammation and host metabolism
disorders; however, the interplay between these outcomes is poorly understood. Using a …

[HTML][HTML] The IRAK1/IRF5 axis initiates IL-12 response by dendritic cells and control of Toxoplasma gondii infection

M Pereira, T Ramalho, WA Andrade, DF Durso… - Cell Reports, 2024 - cell.com
Activation of endosomal Toll-like receptor (TLR) 7, TLR9, and TLR11/12 is a key event in the
resistance against the parasite Toxoplasma gondii. Endosomal TLR engagement leads to …

Mammalian host microRNA response to plasmodial infection: role as therapeutic target and potential biomarker

A Mohanty, V Rajendran - Parasitology Research, 2021 - Springer
The appearance of increasing drug resistance in apicomplexan intracellular Plasmodium
falciparum presents a significant challenge. P. falciparum infection results in cerebral …