Photoinduced chemical transformations have received in recent years a tremendous amount
of attention, providing a plethora of opportunities to synthetic organic chemists. However …

Over the past decade, the landscape of molecular synthesis has gained major impetus by
the introduction of late-stage functionalization (LSF) methodologies. C–H functionalization …

The late stage functionalization (LSF) of complex biorelevant compounds is a powerful tool
to speed up the identification of structure–activity relationships (SARs) and to optimize …

Continuous-flow microreactor technology has been embraced by researchers in academia
and industry due to its excellent transport properties and the increased safety and control …

Biaryl scaffolds are found in natural products and drug molecules and exhibit a wide range
of biological activities. In past decade, the transition metal-catalyzed C–H arylation reaction …

An overview about the potentialities of photocatalytic Hydrogen Atom Transfer (HAT) for the
Late-Stage Functionalization (LSF) of complex molecules is offered. The examined …

A visible-light photoredox-catalyzed method is reported that enables the coupling between
benzylic C–H substrates and N–H azoles. Classically, medicinally relevant N-benzyl azoles …

Owing to the market competitiveness and urgent societal need, an optimum speed of drug
discovery is an important criterion for successful implementation. Despite the rapid ascent of …

Transition metal‐catalysed processes have been widely used for the functionalization of
inert C− H bonds. Strategies for the functionalization of the benzylic C− H position having a …

Herein, we report a photocatalytic procedure that enables the acylation/arylation of
unfunctionalized alkyl derivatives in flow. The method exploits the ability of the …