Endoplasmic reticulum stress (ERS), which refers to a series of adaptive responses to the
disruption of endoplasmic reticulum (ER) homeostasis, occurs when cells are treated by …

Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive interstitial lung disease (ILD)
without an identifiable cause. If not treated after diagnosis, the average life expectancy is 3 …

Mitophagy is a selective autophagic process that degrades dysfunctional mitochondria.
Monofunctional platinum (II) complexes are candidates for anticancer drugs with the …

Pentoxifylline (PTX), a xanthine family molecule and simvastatin (SIM), an anti-
hypercholesterolemic agent, have recently been considered as sensitizers to chemotherapy …

The aim of the current study was to (i) extract isolated fractions of watercress flowers
enriched in polyphenols, phenethyl isothiocyanate and glucosinolates and (ii) characterize …

Pentoxifylline (PTX), as a methylxanthine derivative and nonspecific phosphodiesterase
inhibitor, has the characteristics of anti-inflammatory and partial inflammatory process …

Gastric cancer is a leading cause of cancer-associated mortality worldwide. In studies on the
mechanisms of antigastric cancer drugs, autophagy and endoplasmic reticulum (ER) stress …

Overexposure to manganese (Mn) has been known to induce alpha‐synuclein (α‐Syn)
oligomerization, which is degraded mainly depending on endoplasmic reticulum stress (ER …

Heat shock protein-70kDa (Hsp70) is a member of molecular chaperone family, involved in
the proper folding of various proteins. Hsp70 is important for tumor cell survival and is also …

Two prominent features of tumors that contribute to oncogenic survival signaling are redox
disruption, or oxidative stress phenotype, and high autophagy signaling, making both …