This review focuses on neuropeptides and peptide hormones, the largest and most diverse
class of neuroactive substances, known in Drosophila and other animals to play roles in …

The digestive tract plays a central role in the digestion and absorption of nutrients. Far from
being a passive tube, it provides the first line of defense against pathogens and maintains …

Animals must set behavioural priority in a context-dependent manner and switch from one
behaviour to another at the appropriate moment,–. Here we probe the molecular and …

Lipid metabolism is fundamental to life. In insects, it is critical, during reproduction, flight,
starvation, and diapause. The coordination center for insect lipid metabolism is the fat body …

Sleep is believed to play an important role in memory consolidation. We induced sleep on
demand by expressing the temperature-gated nonspecific cation channel Transient receptor …

The gastrointestinal tract is emerging as a key regulator of appetite and metabolism, but
daunting neuroanatomical complexity has hampered identification of the relevant signals …

Neuropeptides are by far the largest and most diverse group of signaling molecules in
multicellular organisms. They are ancient molecules important in regulating a multitude of …

Neuropeptides modulate neural circuits controlling adaptive animal behaviors and
physiological processes, such as feeding/metabolism, reproductive behaviors, circadian …

Plasticity in animal behaviour relies on the ability to integrate external and internal cues from
the changing environment and hence modulate activity in synaptic circuits of the brain. This …

Lipids are the primary storage molecules and an essential source of energy in insects during
reproduction, prolonged periods of flight, starvation, and diapause. The coordination center …