Aldehyde dehydrogenases and cell proliferation

G Muzio, M Maggiora, E Paiuzzi, M Oraldi… - Free Radical Biology and …, 2012 - Elsevier
Aldehyde dehydrogenases (ALDHs) oxidize aldehydes to the corresponding carboxylic
acids using either NAD or NADP as a coenzyme. Aldehydes are highly reactive aliphatic or …

Emerging roles of aldehyde dehydrogenase isoforms in anti-cancer therapy resistance

M Zanoni, S Bravaccini, F Fabbri, C Arienti - Frontiers in medicine, 2022 - frontiersin.org
Aldehyde dehydrogenases (ALDHs) are a family of detoxifying enzymes often upregulated
in cancer cells and associated with therapeutic resistance. In humans, the ALDH family …

Oxidative and reductive metabolism of lipid-peroxidation derived carbonyls

M Singh, A Kapoor, A Bhatnagar - Chemico-biological interactions, 2015 - Elsevier
Extensive research has shown that increased production of reactive oxygen species (ROS)
results in tissue injury under a variety of pathological conditions and chronic degenerative …

Peroxisome proliferator-activated receptors (PPARs) and oxidative stress in physiological conditions and in cancer

G Muzio, G Barrera, S Pizzimenti - Antioxidants, 2021 - mdpi.com
Peroxisome proliferator-activated receptors (PPARs) belong to the nuclear hormone
receptor superfamily. Originally described as “orphan nuclear receptors”, they can bind both …

Lipid peroxidation: control of cell proliferation, cell differentiation and cell death

G Barrera, S Pizzimenti, MU Dianzani - Molecular aspects of medicine, 2008 - Elsevier
In recent years, it has become evident that lipid peroxidation is not only a mechanism for
deterioration of alimentary oils and fats, but can occur even in living cells, both in …

Recent trends in the advanced analysis of bioactive fatty acids

A Ruiz-Rodriguez, G Reglero, E Ibañez - Journal of pharmaceutical and …, 2010 - Elsevier
The consumption of dietary fats have been long associated to chronic diseases such as
obesity, diabetes, cancer, arthritis, asthma, and cardiovascular disease; although some …

N-Acetylcysteine Reduces Markers of Differentiation in 3T3-L1 Adipocytes

P Calzadilla, D Sapochnik, S Cosentino, V Diz… - International Journal of …, 2011 - mdpi.com
Oxidative stress plays a critical role in the pathogenesis of diabetes, hypertension and
atherosclerosis. Some authors reported that fat accumulation correlates to systemic …

Antitumor activity of Annona squamosa seed oil

Y Chen, Y Chen, Y Shi, C Ma, X Wang, Y Li… - Journal of …, 2016 - Elsevier
Abstract Context Custard apple (Annona squamosa Linn.) is an edible tropical fruit, and its
seeds have been used to treat “malignant sore”(cancer) and other usage as insecticide. A …

Role of aldehyde dehydrogenases in physiopathological processes

JS Rodríguez-Zavala, LF Calleja… - Chemical Research …, 2019 - ACS Publications
Many different diseases are associated with oxidative stress. One of the main consequences
of oxidative stress at the cellular level is lipid peroxidation, from which toxic aldehydes may …

Superpulsed laser irradiation increases osteoblast activity via modulation of bone morphogenetic factors

S Saracino, M Mozzati, G Martinasso… - Lasers in Surgery …, 2009 - Wiley Online Library
Abstract Background and Objective Laser therapy is a new approach applicable in different
medical fields when bone loss occurs, including orthopedics and dentistry. It has also been …