Metallodrugs in cancer nanomedicine

Q Peña, A Wang, O Zaremba, Y Shi… - Chemical Society …, 2022 - pubs.rsc.org
Metal complexes are extensively used for cancer therapy. The multiple variables available
for tuning (metal, ligand, and metal–ligand interaction) offer unique opportunities for drug …

Nanoparticles in clinical translation for cancer therapy

D Mundekkad, WC Cho - International journal of molecular sciences, 2022 - mdpi.com
The advent of cancer therapeutics brought a paradigm shift from conventional therapy to
precision medicine. The new therapeutic modalities accomplished through the properties of …

Progressing nanotechnology to improve targeted cancer treatment: overcoming hurdles in its clinical implementation

M Chehelgerdi, M Chehelgerdi, OQB Allela… - Molecular cancer, 2023 - Springer
The use of nanotechnology has the potential to revolutionize the detection and treatment of
cancer. Developments in protein engineering and materials science have led to the …

In response to precision medicine: Current subcellular targeting strategies for cancer therapy

Z Li, J Zou, X Chen - Advanced Materials, 2023 - Wiley Online Library
Emerging as a potent anticancer treatment, subcellular targeted cancer therapy has drawn
increasing attention, bringing great opportunities for clinical application. Here, two targeting …

Ultrasound‐controlled drug release and drug activation for cancer therapy

L Tu, Z Liao, Z Luo, YL Wu, A Herrmann, S Huo - Exploration, 2021 - Wiley Online Library
Traditional chemotherapy suffers from severe toxicity and side effects that limit its maximum
application in cancer therapy. To overcome this challenge, an ideal treatment strategy would …

Poly (lactic acid)-based microparticles for drug delivery applications: An overview of recent advances

A Vlachopoulos, G Karlioti, E Balla, V Daniilidis… - Pharmaceutics, 2022 - mdpi.com
The sustained release of pharmaceutical substances remains the most convenient way of
drug delivery. Hence, a great variety of reports can be traced in the open literature …

Targeted Drug/Gene/Photodynamic Therapy via a Stimuli‐Responsive Dendritic‐Polymer‐Based Nanococktail for Treatment of EGFR‐TKI‐Resistant Non‐Small‐Cell …

J Huang, C Zhuang, J Chen, X Chen, X Li… - Advanced …, 2022 - Wiley Online Library
Yes‐associated protein (YAP) has been identified as a key driver for epidermal growth factor
receptor‐tyrosine kinase inhibitor (EGFR‐TKI) resistance. Inhibition of YAP expression could …

Progress in polymeric micelles for drug delivery applications

S Kotta, HM Aldawsari, SM Badr-Eldin, AB Nair, K Yt - Pharmaceutics, 2022 - mdpi.com
Polymeric micelles (PMs) have made significant progress in drug delivery applications. A
robust core–shell structure, kinetic stability and the inherent ability to solubilize hydrophobic …

Nanodiscs: a versatile nanocarrier platform for cancer diagnosis and treatment

J Bariwal, H Ma, GA Altenberg, H Liang - Chemical Society Reviews, 2022 - pubs.rsc.org
Cancer therapy is a significant challenge due to insufficient drug delivery to the cancer cells
and non-selective killing of healthy cells by most chemotherapy agents. Nano-formulations …

Block copolymer solution self‐assembly: Recent advances, emerging trends, and applications

M Karayianni, S Pispas - Journal of Polymer Science, 2021 - Wiley Online Library
The self‐assembly process of block copolymers (BCPs) in solution has been at the focus of
extended scientific research over the past several decades owing to the astonishing …