Until recently, the standard of care (SOC) for patients with chronic hepatitis C virus (HCV)
infection has consisted of a combination of pegylated interferon-N1 plus ribavirin …

IBD is a spectrum of chronic disorders that constitute an important health problem
worldwide. The hunt for genetic determinants of disease onset and course has culminated in …

Background & Aims As more treatment options for inflammatory bowel diseases become
available, it is important to identify patients most likely to respond to different therapies. We …

Intestinal Mϕ play an important role in maintaining gut homeostasis. However, little is known
about these cells, their precursors, and their role in intestinal inflammation. Here, we …

METHODS Patients Patients with complete 15-year follow-up records were selected from the
MICISTA Registry. This tertiary clinical database of more than 7000 patients with …

Background and aims Clinical management of inflammatory bowel diseases (IBD), new
treatment modalities and the potential impact of personalised medicine remain topics of …

Crohn's disease is a chronic inflammatory disorder that follows a progressive and
destructive course. Ultimately, uncontrolled inflammation leads to bowel damage from …

Crohn disease is a chronic disorder characterized by episodes of epithelial inflammation in
the gastrointestinal tract for which there is no cure. The prevalence of Crohn disease …

Monoclonal antibodies to tumor necrosis factor (TNF) have become a mainstay of the
therapeutic armamentarium in inflammatory bowel disease (IBD) over the last 15 years …

Inflammatory bowel diseases (IBDs) are chronic and impose significant, multidimensional
burdens on patients and health care systems. The increasing prevalence of IBD will only …