Bright and dark sides of nitric oxide in ischemic brain injury
C Iadecola - Trends in neurosciences, 1997 - cell.com
There is increasing evidence that nitric oxide (NO), a free radical that can act both as a
signaling molecule and a neurotoxin, is involved in the mechanisms of cerebral ischemia …
signaling molecule and a neurotoxin, is involved in the mechanisms of cerebral ischemia …
[PDF][PDF] The retroviral enzymes
RA Katz, AM Skalka - Annual review of biochemistry, 1994 - researchgate.net
least four activities:(a) protease (PR),(b) the polymerase and (c) nuclease H (RNase H)
activities of reverse transcriptase (RT), and integrase (IN). These activities are required for …
activities of reverse transcriptase (RT), and integrase (IN). These activities are required for …
LTRPC2 Ca2+-permeable channel activated by changes in redox status confers susceptibility to cell death
Y Hara, M Wakamori, M Ishii, E Maeno, M Nishida… - Molecular cell, 2002 - cell.com
Redox status changes exert critical impacts on necrotic/apoptotic and normal cellular
processes. We report here a widely expressed Ca 2+-permeable cation channel, LTRPC2 …
processes. We report here a widely expressed Ca 2+-permeable cation channel, LTRPC2 …
Nitric oxide protects against cellular damage and cytotoxicity from reactive oxygen species.
DA Wink, I Hanbauer, MC Krishna… - Proceedings Of the …, 1993 - National Acad Sciences
Nitric oxide, NO, which is generated by various components of the immune system, has
been presumed to be cytotoxic. However, NO has been proposed to be protective against …
been presumed to be cytotoxic. However, NO has been proposed to be protective against …
[HTML][HTML] Roles of nitric oxide in brain hypoxia-ischemia
JP Bolaños, A Almeida - Biochimica et Biophysica Acta (BBA) …, 1999 - Elsevier
A large body of evidence has appeared over the last 6 years suggesting that nitric oxide
biosynthesis is a key factor in the pathophysiological response of the brain to hypoxia …
biosynthesis is a key factor in the pathophysiological response of the brain to hypoxia …
Nitric oxide synthase inhibition and cerebrovascular regulation
C Iadecola, DA Pelligrino… - Journal of Cerebral …, 1994 - journals.sagepub.com
There is increasing evidence that nitric oxide (NO) is an important molecular messenger
involved in a wide variety of biological processes. Recent data suggest that NO is also …
involved in a wide variety of biological processes. Recent data suggest that NO is also …
Normal and abnormal calcium homeostasis in neurons: a basis for the pathophysiology of traumatic and ischemic central nervous system injury
M Tymianski, CH Tator - Neurosurgery, 1996 - journals.lww.com
Abstract CLINICAL RECOVERY AFTER central nervous system (CNS) trauma or ischemia
may be limited by a neural injury process that is triggered and perpetuated at the cellular …
may be limited by a neural injury process that is triggered and perpetuated at the cellular …
Reduced brain edema and infarction volume in mice lacking the neuronal isoform of nitric oxide synthase after transient MCA occlusion
H Hara, PL Huang, N Panahian… - Journal of Cerebral …, 1996 - journals.sagepub.com
Infarct volume and edema were assessed after transient focal ischemia in mice lacking
neuronal nitric oxide synthase (NOS) gene expression. With use of an 8–0 coated …
neuronal nitric oxide synthase (NOS) gene expression. With use of an 8–0 coated …
Nitric oxide: a neural messenger.
SR Jaffrey, SH Snyder - Annual review of cell and developmental …, 1995 - europepmc.org
Nitric oxide (NO) is a messenger molecule that is now a well established neurotransmitter in
the central and peripheral nervous systems. NO was initially characterized as the" …
the central and peripheral nervous systems. NO was initially characterized as the" …
Neural roles for heme oxygenase: contrasts to nitric oxide synthase
DE Barañano, SH Snyder - Proceedings of the National …, 2001 - National Acad Sciences
The heme oxygenase (HO) and nitric oxide (NO) synthase (NOS) systems display notable
similarities as well as differences. HO and NOS are both oxidative enzymes using NADPH …
similarities as well as differences. HO and NOS are both oxidative enzymes using NADPH …