The chemistry of hapalindoles, fischerindoles, ambiguines, and welwitindolinones
Isolated from diverse cyanobacteria, the hapalindole family of indole alkaloids comprises
over 80 interrelated natural products. The family is further divided into several subclasses …
over 80 interrelated natural products. The family is further divided into several subclasses …
Total Synthesis of Oxidized Welwitindolinones and (−)-N-Methylwelwitindolinone C Isonitrile
KW Quasdorf, AD Huters, MW Lodewyk… - Journal of the …, 2012 - ACS Publications
We report the total synthesis of (−)-N-methylwelwitindolinone C isonitrile, in addition to the
total syntheses of the 3-hydroxylated welwitindolinones. Our routes to these elusive natural …
total syntheses of the 3-hydroxylated welwitindolinones. Our routes to these elusive natural …
Total Synthesis of (−)-N-Methylwelwitindolinone C Isothiocyanate
AD Huters, KW Quasdorf, ED Styduhar… - Journal of the American …, 2011 - ACS Publications
We report the first total synthesis of (−)-N-methylwelwitindolinone C isothiocyanate. Our
route features a number of key transformations, including an indolyne cyclization to …
route features a number of key transformations, including an indolyne cyclization to …
Direct photo-induced reductive Heck cyclization of indoles for the efficient preparation of polycyclic indolinyl compounds
The photo-induced cleavage of C (sp2)–Cl bonds is an appealing synthetic tool in organic
synthesis, but usually requires the use of high UV light, photocatalysts and/or …
synthesis, but usually requires the use of high UV light, photocatalysts and/or …
Total Synthesis of N-Methylwelwitindolinone D Isonitrile
Described is a concise total synthesis of N-methylwelwitindolinone D isonitrile, the first in a
family of complex bicyclo [4.3. 1] decane-containing indole alkaloids to yield to synthesis …
family of complex bicyclo [4.3. 1] decane-containing indole alkaloids to yield to synthesis …
Diastereoselective Synthesis of Cycloheptannelated Indoles via Lewis-Acid-Catalyzed (4+ 3)-Cyclization of Donor–Acceptor Cyclopropanes
BQ Li, ZW Qiu, AJ Ma, JB Peng, N Feng, JY Du… - Organic …, 2020 - ACS Publications
An efficient and straightforward Lewis-acid-mediated stereoselective (4+ 3)-cyclization of
indole-substituted alkylidene malonates and donor–acceptor cyclopropanes has been …
indole-substituted alkylidene malonates and donor–acceptor cyclopropanes has been …
Total syntheses of the elusive welwitindolinones with bicyclo [4.3. 1] cores
AD Huters, ED Styduhar… - Angewandte Chemie …, 2012 - Wiley Online Library
Abstract The welwitindolinones with bicyclo [4.3. 1] cores are a class of natural products that
have attracted tremendous interest from the synthetic community because of their fascinating …
have attracted tremendous interest from the synthetic community because of their fascinating …
Total Synthesis of (−)-N-Methylwelwitindolinone B Isothiocyanate via a Chlorinative Oxabicycle Ring-Opening Strategy
Total Synthesis of (−)-N-Methylwelwitindolinone B Isothiocyanate via a Chlorinative Oxabicycle
Ring-Opening Strategy | Journal of the American Chemical Society ACS ACS Publications …
Ring-Opening Strategy | Journal of the American Chemical Society ACS ACS Publications …
A Unified Route to the Welwitindolinone Alkaloids: Total Syntheses of (−)-N-Methylwelwitindolinone C Isothiocyanate, (−)-N-Methylwelwitindolinone C Isonitrile, and (−)-3 …
KM Allan, K Kobayashi, VH Rawal - Journal of the American …, 2012 - ACS Publications
As part of a comprehensive strategy to the welwitindolinone alkaloids possessing a bicyclo
[4.3. 1] decane core, we report herein concise asymmetric total syntheses of (−)-N …
[4.3. 1] decane core, we report herein concise asymmetric total syntheses of (−)-N …
Formal syntheses of naturally occurring welwitindolinones
T Fu, WT McElroy, M Shamszad, SF Martin - Organic letters, 2012 - ACS Publications
The formal syntheses of N-methylwelwitindolinone C isothiocyanate, N-
methylwelwitindolinone C isonitrile, N-methylwelwitindolinone D isonitrile, 3-hydroxy-N …
methylwelwitindolinone C isonitrile, N-methylwelwitindolinone D isonitrile, 3-hydroxy-N …