Preparation of alginate-based biomaterials and their applications in biomedicine
H Zhang, J Cheng, Q Ao - Marine Drugs, 2021 - mdpi.com
Alginates are naturally occurring polysaccharides extracted from brown marine algae and
bacteria. Being biocompatible, biodegradable, non-toxic and easy to gel, alginates can be …
bacteria. Being biocompatible, biodegradable, non-toxic and easy to gel, alginates can be …
Functional and biomimetic materials for engineering of the three-dimensional cell microenvironment
The cell microenvironment has emerged as a key determinant of cell behavior and function
in development, physiology, and pathophysiology. The extracellular matrix (ECM) within the …
in development, physiology, and pathophysiology. The extracellular matrix (ECM) within the …
Advances in multicellular spheroids formation
Three-dimensional multicellular spheroids (MCSs) have a complex architectural structure,
dynamic cell–cell/cell–matrix interactions and bio-mimicking in vivo microenvironment. As a …
dynamic cell–cell/cell–matrix interactions and bio-mimicking in vivo microenvironment. As a …
Alginate-based biomaterials for regenerative medicine applications
Alginate is a natural polysaccharide exhibiting excellent biocompatibility and
biodegradability, having many different applications in the field of biomedicine. Alginate is …
biodegradability, having many different applications in the field of biomedicine. Alginate is …
Injectable stem cell‐laden photocrosslinkable microspheres fabricated using microfluidics for rapid generation of osteogenic tissue constructs
X Zhao, S Liu, L Yildirimer, H Zhao… - Advanced Functional …, 2016 - Wiley Online Library
Direct injection is a minimally invasive method of stem cell transplantation for numerous
injuries and diseases. However, despite its promising potential, its clinical translation is …
injuries and diseases. However, despite its promising potential, its clinical translation is …
Three‐dimensional models of cancer for pharmacology and cancer cell biology: capturing tumor complexity in vitro/ex vivo
JA Hickman, R Graeser, R de Hoogt… - Biotechnology …, 2014 - Wiley Online Library
Cancers are complex and heterogeneous pathological “organs” in a dynamic interplay with
their host. Models of human cancer in vitro, used in cancer biology and drug discovery, are …
their host. Models of human cancer in vitro, used in cancer biology and drug discovery, are …
Human pluripotent stem cell culture: considerations for maintenance, expansion, and therapeutics
Human pluripotent stem cells (hPSCs) provide powerful resources for application in
regenerative medicine and pharmaceutical development. In the past decade, various …
regenerative medicine and pharmaceutical development. In the past decade, various …
A fully defined and scalable 3D culture system for human pluripotent stem cell expansion and differentiation
Y Lei, DV Schaffer - … of the National Academy of Sciences, 2013 - National Acad Sciences
Human pluripotent stem cells (hPSCs), including human embryonic stem cells and induced
pluripotent stem cells, are promising for numerous biomedical applications, such as cell …
pluripotent stem cells, are promising for numerous biomedical applications, such as cell …
Process engineering of human pluripotent stem cells for clinical application
Human pluripotent stem cells (hPSCs), including embryonic and induced pluripotent stem
cells, constitute an extremely attractive tool for cell therapy. However, flexible platforms for …
cells, constitute an extremely attractive tool for cell therapy. However, flexible platforms for …
Advances in cell culture: anchorage dependence
OW Merten - … Transactions of the Royal Society B …, 2015 - royalsocietypublishing.org
Anchorage-dependent cells are of great interest for various biotechnological applications.(i)
They represent a formidable production means of viruses for vaccination purposes at very …
They represent a formidable production means of viruses for vaccination purposes at very …