Autophagy and cancer drug resistance in dialogue: pre-clinical and clinical evidence
Y Qin, M Ashrafizadeh, V Mongiardini, B Grimaldi… - Cancer letters, 2023 - Elsevier
The emergence of drug resistance is a major challenge for oncologists. Resistance can be
categorized as acquired or intrinsic; the alteration of several biological mechanisms …
categorized as acquired or intrinsic; the alteration of several biological mechanisms …
Long non-coding RNAs in lung cancer: Unraveling the molecular modulators of MAPK signaling
Lung cancer (LC) continues to pose a significant global medical burden, necessitating a
comprehensive understanding of its molecular foundations to establish effective treatment …
comprehensive understanding of its molecular foundations to establish effective treatment …
Tumor hypoxia: From basic knowledge to therapeutic implications
Diminished oxygen availability, termed hypoxia, within solid tumors is one of the most
common characteristics of cancer. Hypoxia shapes the landscape of the tumor …
common characteristics of cancer. Hypoxia shapes the landscape of the tumor …
[HTML][HTML] Progress in targeting PTEN/PI3K/Akt axis in glioblastoma therapy: Revisiting molecular interactions
M Hashemi, S Etemad, S Rezaei, S Ziaolhagh… - Biomedicine & …, 2023 - Elsevier
Glioblastoma (GBM) is one of the most malignant cancers of central nervous system and due
to its sensitive location, surgical resection has high risk and therefore, chemotherapy and …
to its sensitive location, surgical resection has high risk and therefore, chemotherapy and …
Long non-coding RNAs (lncRNAs); roles in tumorigenesis and potentials as biomarkers in cancer diagnosis
S Najafi, SH Khatami, M Khorsand, Z Jamali… - Experimental cell …, 2022 - Elsevier
New research has indicated that long non-coding RNAs (lncRNAs) play critical roles in a
broad range of biological processes, including the pathogenesis of many complex human …
broad range of biological processes, including the pathogenesis of many complex human …
LncRNA in tumorigenesis of non-small-cell lung cancer: From bench to bedside
Q Hu, H Ma, H Chen, Z Zhang, Q Xue - Cell death discovery, 2022 - nature.com
Lung cancer has been one of the leading causes of cancer-related death worldwide, and
non-small-cell lung cancer (NSCLC) accounts for the majority of lung cancer morbidity, yet …
non-small-cell lung cancer (NSCLC) accounts for the majority of lung cancer morbidity, yet …
[HTML][HTML] SOX2 function in cancers: Association with growth, invasion, stemness and therapy response
S Mirzaei, MDA Paskeh, M Entezari… - Biomedicine & …, 2022 - Elsevier
Cancer is a leading cause of death worldwide and around 10 million deaths in 2020 were
related to cancer. There are a number of therapeutic modalities for cancer such as …
related to cancer. There are a number of therapeutic modalities for cancer such as …
Exosome nanovesicles as potential biomarkers and immune checkpoint signaling modulators in lung cancer microenvironment: recent advances and emerging …
Lung cancer remains the leading cause of cancer-related deaths globally, and the survival
rate remains low despite advances in diagnosis and treatment. The progression of lung …
rate remains low despite advances in diagnosis and treatment. The progression of lung …
Noncoding RNA as an influential epigenetic modulator with promising roles in cancer therapeutics
The epigenetic landscape has an important role in cellular homeostasis and its deregulation
leads to cancer. Noncoding (nc) RNA networks function as major regulators of cellular …
leads to cancer. Noncoding (nc) RNA networks function as major regulators of cellular …
Liquid biopsy on the horizon in immunotherapy of non-small cell lung cancer: current status, challenges, and perspectives
Y Yang, H Liu, Y Chen, N Xiao, Z Zheng, H Liu… - Cell Death & …, 2023 - nature.com
Non-small cell lung cancer (NSCLC) is one of the most threatening malignancies to human
health and life. In most cases, patients with NSCLC are already at an advanced stage when …
health and life. In most cases, patients with NSCLC are already at an advanced stage when …