Traumatic brain injury (TBI) contributes a major cause of death, disability, and mental health
disorders. Most TBI patients suffer long-term post-traumatic stress disorder, cognitive …

Traumatic brain injury (TBI) is a major public health challenge that is also the third leading
cause of death worldwide. It is also the leading cause of long-term disability in children and …

The blood-brain barrier (BBB) constitutes a neurovascular unit formed by microvascular
endothelial cells, pericytes, and astrocytes. Brain pericytes are important regulators of BBB …

Recent studies from our group and others have demonstrated that oxidative stress, Ca 2+
signaling, and neuroinflammation are major mechanisms contributing to post-traumatic …

Several studies have documented the role of hyper-activation of extracellular signal-
regulated kinases (ERK) in Autism pathogenesis. Alpha-mangostin (AMG) is a …

In this review, we discuss the possibility and feasibility of nuclear factor erythroid 2-related
factor 2 (Nrf2) as a therapeutic target to minimize the devastating effects of a brain injury. To …

Accumulation of extracellular amyloid-β (Aβ) in hippocampal subregions is a hallmark of
Alzheimer's disease (AD), which promotes neuronal apoptosis, potentiates cognitive decline …

Alzheimer's disease (AD) is the most common cause of dementia, the chronic and
progressive deterioration of memory and cognitive abilities. AD can be pathologically …

Repetitive mild traumatic brain injury (r-mTBI), commonly experienced by athletes and
military personnel, causes changes in multiple intracellular pathways, one of which involves …

The Wnt pathway, which comprises the canonical and non-canonical pathways, is an
evolutionarily conserved mechanism that regulates crucial biological aspects throughout the …