Bone grafts have been predominated used to treat bone defects, delayed union or non-
union, and spinal fusion in orthopaedic clinically for a period of time, despite the emergency …

Background context Increasingly, reports of frequent and occasionally catastrophic
complications associated with use of recombinant human bone morphogenetic protein-2 …

Background The comparative effectiveness of performing instrumented (rigid pedicle screws
affixed to titanium alloy rods) lumbar spinal fusion in addition to decompressive laminectomy …

Bone grafting is a commonly performed surgical procedure to augment bone regeneration in
a variety of cases in orthopaedic and maxillofacial surgery. Autologous bone graft remains to …

Purpose Lumbar interbody fusion (LIF) is a treatment option for low back pain secondary to
lumbar instability and/or deformity. This review highlights recent studies of surgical …

Background: Recombinant human bone morphogenetic protein-2 (rhBMP-2) is widely used
to promote fusion in spinal surgery, but its safety has been questioned. Purpose: To evaluate …

Regeneration of bone and cartilage defects can be accelerated by localized delivery of
appropriate growth factors incorporated within biodegradable carriers. The carrier …

Context No national data exist to examine use of bone-morphogenetic proteins (BMPs) in
spinal fusion surgery. Objective To determine the patterns of use and rates of complications …

Bioceramics, such as calcium phosphate ceramics and cements and silica-based glasses,
are widely used as components of implants for bone and teeth restoration. Nowadays, the …

Over the past several decades, recombinant human bone morphogenetic proteins (rhBMPs)
have been the most extensively studied and widely used osteoinductive agents for clinical …