The ability of pathogenic fungi to switch between a multicellular hyphal and unicellular yeast
growth form is a tightly regulated process known as dimorphic switching. Dimorphic …

The recognition of fungal cells by the host immune system is key during the establishment of
a protective anti-fungal response. Even though the immune system has evolved a vast …

Fungal pathogens must assimilate local nutrients to establish an infection in their
mammalian host. We focus on carbon, nitrogen, and micronutrient assimilation mechanisms …

Fungi are adept at changing their cell shape and developmental program in response to
signals in their surroundings. Here we focus on a group of evolutionarily related fungal …

Background Aspergillus fumigatus is the most common etiologic agent of invasive
aspergillosis in immunocompromised patients. Several studies have addressed the …

An efficient oxidative stress response is important to the fungal pathogen Paracoccidioides
to survive within the human host. In this study, oxidative stress was mimicked by exposure of …

Virulence of Cryptococcus neoformans for mammals, and in particular its intracellular style,
was proposed to emerge from evolutionary pressures on its natural environment by …

Macrophages are key players during Paracoccidioides brasiliensis infection. However, the
relative contribution of the fungal response to counteracting macrophage activity remains …

Paracoccidioides spp. are dimorphic fungal pathogens responsible for one of the most
relevant systemic mycoses in Latin America, paracoccidioidomycosis (PCM). Their exact …

Human fungal pathogens are a deadly and underappreciated risk to global health that most
severely affect immunocompromised individuals. A virulence attribute shared by some of the …