Obesity and bone: a complex relationship

G Rinonapoli, V Pace, C Ruggiero, P Ceccarini… - International journal of …, 2021 - mdpi.com
There is a large literature on the relationship between obesity and bone. What we can
conclude from this review is that the increase in body weight causes an increase in BMD …

Inflammatory links between high fat diets and diseases

Y Duan, L Zeng, C Zheng, B Song, F Li… - Frontiers in …, 2018 - frontiersin.org
In recent years, chronic overnutrition, such as consumption of a high-fat diet (HFD), has
been increasingly viewed as a significant modifiable risk factor for diseases such as …

Fat, sugar, and bone health: a complex relationship

L Tian, X Yu - Nutrients, 2017 - mdpi.com
With people aging, osteoporosis is expected to increase notably. Nutritional status is a
relatively easily-modified risk factor, associated with many chronic diseases, and is involved …

Do polyunsaturated fatty acids protect against bone loss in our aging and osteoporotic population?

K Martyniak, F Wei, A Ballesteros, T Meckmongkol… - Bone, 2021 - Elsevier
Age-related bone loss is inevitable in both men and women and there will soon be more
people of extreme old age than ever before. Osteoporosis is a common chronic disease and …

Effects of metabolic syndrome on bone mineral density, histomorphometry and remodelling markers in male rats

SK Wong, KY Chin, FH Suhaimi, F Ahmad… - PLoS …, 2018 - journals.plos.org
This study aimed to evaluate the effects of metabolic syndrome (MetS) induced by high-
carbohydrate high-fat (HCHF) diet on bone mineral density (BMD), histomorphometry and …

Establishment of high-fat diet-induced obesity and insulin resistance model in rats

XY Zhang, CC Guo, YX Yu, L Xie… - … da xue xue bao. Yi xue …, 2020 - europepmc.org
Objective To investigate the appropriate conditions and duration for establishing a high-fat
diet-induced obesity and insulin resistance model in rats. Methods Forty-five 6-week-old …

Arachidonic acid exacerbates diet-induced obesity and reduces bone mineral content without impacting bone strength in growing male rats

IL Mak, P Lavery, S Agellon, F Rauch… - The Journal of nutritional …, 2019 - Elsevier
Long-chain polyunsaturated fatty acids modulate bone mass and adipocyte metabolism.
Arachidonic acid (AA, C20: 4 n-6) is elevated in obesity and postulated to stimulate bone …

Weight change patterns across adulthood in relation to osteoporosis and fracture among non-obese individuals

P Jia, J Yuan - Archives of Osteoporosis, 2023 - Springer
Weight change was an influencing factor of osteoporosis and fracture in a controversial way.
Based on a nationally representative data, we found that weight change from obesity in …

Ketogenic diet compromises both cancellous and cortical bone mass in mice

X Wu, Z Huang, X Wang, Z Fu, J Liu, Z Huang… - Calcified Tissue …, 2017 - Springer
To clarify osteoporotic effects of ketogenic diet (KD) on cancellous and cortical bone
compared with ovariectomy (OVX) in mice. Forty female C57BL/6J 8-week-old mice were …

[HTML][HTML] Changes in bone mass associated with obesity and weight loss in humans: Applicability of animal models

VFH Jensen, AM Mølck, M Dalgaard, FE McGuigan… - Bone, 2021 - Elsevier
The implications of obesity and weight loss for human bone health are not well understood.
Although the bone changes associated with weight loss are similar in humans and rodents …