Mammalian/mechanistic target of rapamycin (mTOR) is a serine-threonine kinase that
controls several important aspects of mammalian cell function. mTOR activity is modulated …

The control of body and organ growth is essential for the development of adults with proper
size and proportions, which is important for survival and reproduction. In animals, adult body …

Target of rapamycin (TOR) is an evolutionarily conserved protein kinase that plays a central
role in both plants and animals, despite their distinct developmental programs and survival …

We previously reported a CRISPR-mediated knock-in strategy into introns of Drosophila
genes, generating an attP-FRT-SA-T2A-GAL4-polyA-3XP3-EGFP-FRT-attP transgenic …

The multidomain target of rapamycin (TOR) is an atypical serine/threonine protein kinase
resembling phosphatidylinositol lipid kinases, but retains high sequence identity and serves …

Pontin (RUVBL1, TIP49, TIP49a, Rvb1) and Reptin (RUVBL2, TIP48, TIP49b, Rvb2) are
highly conserved ATPases of the AAA+ (ATPases Associated with various cellular Activities) …

Target of rapamycin (TOR) is an evolutionarily conserved protein kinase that functions as a
central signaling hub to integrate diverse internal and external cues to precisely orchestrate …

Hsp90 is a ubiquitous molecular chaperone involved in many cell signaling pathways, and
its interactions with specific chaperones and cochaperones determines which client proteins …

The target of rapamycin (TOR) is an evolutionarily-conserved serine/threonine kinase that
senses and integrates signals from the environment to coordinate developmental and …

We generated two new genetic tools to efficiently tag genes in Drosophila. The first, Double
Header (DH) utilizes intronic MiMIC/CRIMIC insertions to generate artificial exons for GFP …