Targeting mycobacterial membranes and membrane proteins: Progress and limitations
Among the various bacterial infections, tuberculosis continues to hold center stage. Its
causative agent, Mycobacterium tuberculosis, possesses robust defense mechanisms …
causative agent, Mycobacterium tuberculosis, possesses robust defense mechanisms …
Recent advancements and developments in search of anti-tuberculosis agents: a quinquennial update and future directions
Tuberculosis (TB) has been considered as the highly chronic, contagious and infectious
disorder caused by Mycobacterium tuberculosis (Mtb). Every year more than 10 million …
disorder caused by Mycobacterium tuberculosis (Mtb). Every year more than 10 million …
Synthetic account of indoles in search of potential anti-mycobacterial agents: a review and future insights
KA Bhakhar, DK Sureja, TM Dhameliya - Journal of Molecular Structure, 2022 - Elsevier
Indole, an aza-heterocyclic scaffold, has been found one of the most privileged scaffolds in
heterocyclic chemistry and drug discovery. Efforts have been made to provide the complete …
heterocyclic chemistry and drug discovery. Efforts have been made to provide the complete …
[HTML][HTML] Indole: A promising scaffold for the discovery and development of potential anti-tubercular agents
Indole-containing small molecules have been reported to have diverse pharmacological
activities. The aromatic heterocyclic scaffold, which resembles various protein structures …
activities. The aromatic heterocyclic scaffold, which resembles various protein structures …
Indole‐2‐carboxamides as New Anti‐Mycobacterial Agents: Design, Synthesis, Biological Evaluation and Molecular Modeling against mmpL3
KA Bhakhar, PV Vaghela, SD Varakala… - …, 2022 - Wiley Online Library
Tuberculosis (TB), an airborne disease caused by Mycobacterium tuberculosis, has infected
millions of people and been responsible for their deaths. Toward the anti‐TB endeavor, the …
millions of people and been responsible for their deaths. Toward the anti‐TB endeavor, the …
[HTML][HTML] Synthesis and Biological Evaluation of Benzo[b]thiophene Acylhydrazones as Antimicrobial Agents against Multidrug-Resistant Staphylococcus aureus
T Barbier, A Barbry, J Magand, C Badiou, F Davy… - Biomolecules, 2022 - mdpi.com
The benzo [b] thiophene nucleus and the acylhydrazone functional group were combined to
prepare three new series of compounds for screening against Staphylococcus aureus. The …
prepare three new series of compounds for screening against Staphylococcus aureus. The …
Enhancing the CO2 Adsorption with Dual Functionalized Coconut Shell-Hydrochar using Chlorella Microalgae and Metal Oxide: Synthesis, Physicochemical …
NZM Azmi, A Buthiyappan, MFA Patah… - Journal of Cleaner …, 2024 - Elsevier
This study aims to develop an inexpensive, environmentally-friendly adsorbent for capturing
CO 2 using coconut shells, widely abundant in Asian agricultural waste. The raw coconut …
CO 2 using coconut shells, widely abundant in Asian agricultural waste. The raw coconut …
Microwave-assisted organic synthesis, antimycobacterial activity, structure–activity relationship and molecular docking studies of some novel indole-oxadiazole …
Multidrug-resistant tuberculosis (MDR-TB) is a severe threat to mankind because most drugs
are ineffective in inhibiting tubercular strains. Due to the increase of MDR-TB, many first and …
are ineffective in inhibiting tubercular strains. Due to the increase of MDR-TB, many first and …
A squaramide-catalysed asymmetric cascade Michael addition/acyl transfer reaction between unsaturated benzothiophenones and α-nitroketones
C Niu, DM Du - Organic & Biomolecular Chemistry, 2022 - pubs.rsc.org
An efficient and practical organocatalytic asymmetric strategy was developed using
unsaturated benzothiophenones and α-nitroketones catalysed by bifunctional squaramide …
unsaturated benzothiophenones and α-nitroketones catalysed by bifunctional squaramide …
Diastereoselective Construction of CF3‐Containing Bispiro[isoquinolone‐pyrrolidine‐benzothiophenone]s through 1,3‐Dipolar Cycloaddition
C Niu, DM Du - European Journal of Organic Chemistry, 2022 - Wiley Online Library
A new protocol to access CF3‐containing bispiro [isoquinolone‐pyrrolidine‐
benzothiophenone] s was described. A series of 1, 3‐dipoles were synthesized from …
benzothiophenone] s was described. A series of 1, 3‐dipoles were synthesized from …