Vax-Innate: improving therapeutic cancer vaccines by modulating T cells and the tumour microenvironment

F Baharom, D Hermans, L Delamarre… - Nature Reviews …, 2024 - nature.com
T cells have a critical role in mediating antitumour immunity. The success of immune
checkpoint inhibitors (ICIs) for cancer treatment highlights how enhancing endogenous T …

Artificial intelligence and neoantigens: paving the path for precision cancer immunotherapy

A Bulashevska, Z Nacsa, F Lang, M Braun… - Frontiers in …, 2024 - frontiersin.org
Cancer immunotherapy has witnessed rapid advancement in recent years, with a particular
focus on neoantigens as promising targets for personalized treatments. The convergence of …

[HTML][HTML] Bridging the Gap from Proteomics Technology to Clinical Application: Highlights from the 68th Benzon Foundation Symposium

V Albrecht, J Müller-Reif, TM Nordmann, A Mund… - Molecular & Cellular …, 2024 - Elsevier
SUMMARY The 68th Benzon Foundation Symposium brought together leading experts to
explore the integration of mass spectrometry (MS)-based proteomics and artificial …

Graph-pMHC: graph neural network approach to MHC class II peptide presentation and antibody immunogenicity

WJ Thrift, J Perera, S Cohen… - Briefings in …, 2024 - academic.oup.com
Antigen presentation on MHC class II (pMHCII presentation) plays an essential role in the
adaptive immune response to extracellular pathogens and cancerous cells. But it can also …

Me, the hill and my browser–investigating the role of time in posthuman interaction

P Ciobanu, O Juhlin - Nordic Human-Computer Interaction Conference, 2022 - dl.acm.org
Despite the growing concerns related to environmental disruptions, such as forest fires and
floods, our interaction with nature has become increasingly distant. The belief is that this is …

Pep2Vec: An Interpretable Model for Peptide-MHC Presentation Prediction and Contaminant Identification in Ligandome Datasets

WJ Thrift, Q Broadwell, J Perera, NW Lounsbury… - bioRxiv, 2024 - biorxiv.org
As personalized cancer vaccines advance, precise modeling of antigen presentation by
MHC class I and II is crucial. High-quality training data is essential for clinical models …

Material Deconstructions of Time: Posthumanist Interventions Through Media Art

P Ciobanu, Y Fernaeus - ACM Transactions on Computer-Human Interaction - dl.acm.org
The topic of time and how it can be unpacked, deconstructed, and designed with is
fundamental to HCI, but it is also extensively engaged within artistic practice. By analysing a …