Melatonin therapy for REM sleep behavior disorder: a critical review of evidence

IR McGrane, JG Leung, EKS Louis, BF Boeve - Sleep medicine, 2015 - Elsevier
Rapid eye movement (REM) sleep behavior disorder (RBD) is a parasomnia associated with
dream enactment often involving violent or potentially injurious behaviors during REM sleep …

The clinical and pathophysiological relevance of REM sleep behavior disorder in neurodegenerative diseases

A Iranzo, J Santamaria, E Tolosa - Sleep medicine reviews, 2009 - Elsevier
REM sleep behavior disorder (RBD) is characterized by vigorous movements associated
with unpleasant dreams and increased electromyographic activity during REM sleep …

The clinical phenotype of idiopathic rapid eye movement sleep behavior disorder at presentation: a study in 203 consecutive patients

A Fernández-Arcos, A Iranzo, M Serradell, C Gaig… - Sleep, 2016 - academic.oup.com
Objective To describe the clinical phenotype of idiopathic rapid eye movement (REM) sleep
behavior disorder (IRBD) at presentation in a sleep center. Methods Clinical history review …

Rapid eye movement sleep behavior disorder: devising controlled active treatment studies for symptomatic and neuroprotective therapy—a consensus statement from …

CH Schenck, JY Montplaisir, B Frauscher, B Hogl… - Sleep medicine, 2013 - Elsevier
Objectives We aimed to provide a consensus statement by the International Rapid Eye
Movement Sleep Behavior Disorder Study Group (IRBD-SG) on devising controlled active …

[HTML][HTML] MicroRNAs in cerebrospinal fluid as potential biomarkers for Parkinson's disease and multiple system atrophy

TM Marques, HB Kuiperij, IB Bruinsma… - Molecular …, 2017 - Springer
Parkinson's disease (PD) and multiple system atrophy (MSA) are both part of the spectrum of
neurodegenerative movement disorders and α-synucleinopathies with overlap of symptoms …

[HTML][HTML] Parasomnias: an updated review

MJ Howell - Neurotherapeutics, 2012 - Elsevier
Parasomnias are abnormal behaviors emanating from or associated with sleep.
Sleepwalking and related disorders result from an incomplete dissociation of wakefulness …

Clinical trials in REM sleep behavioural disorder: challenges and opportunities

A Videnovic, YES Ju, I Arnulf… - Journal of Neurology …, 2020 - jnnp.bmj.com
The rapid eye movement sleep behavioural disorder (RBD) population is an ideal study
population for testing disease-modifying treatments for synucleinopathies, since RBD …

Dreams in patients with sleep disorders

M Schredl - Sleep medicine reviews, 2009 - Elsevier
Dreaming is defined as mental activity which occurs during sleep. This review will focus on
sleep disorders which have been studied in relation to dreaming: insomnia, sleep apnea …

Beyond tremor and rigidity: non-motor features of Parkinson's disease

M Löhle, A Storch, H Reichmann - Journal of neural transmission, 2009 - Springer
Parkinson's disease (PD) is the second most common neurodegenerative disease and
primarily considered as a movement disorder defined by the presence of motor symptoms …

A novel therapy for REM sleep behavior disorder (RBD)

MJ Howell, PA Arneson, CH Schenck - Journal of Clinical Sleep …, 2011 - jcsm.aasm.org
Study Objectives: RBD may result in sleep related injury (SRI) particularly if a patient exits
the bed during dream enactment behavior (DEB). The complex auditory processing and low …