Simple Summary Hepatocellular carcinoma (HCC) constitutes a major health burden,
accounting for> 80% of primary liver cancers globally. Inflammation has come into the …

Chronic liver disease (CLD) is a growing health concern which accounts for two million
deaths per year. Obesity, alcohol overconsumption, and progressive cholestasis are …

Osteopontin characterizes bile duct–associated macrophages a... : Hepatology Osteopontin
characterizes bile duct–associated macrophages and correlates with liver fibrosis severity in …

Abstract Aflatoxin B1 (AFB1) and fumonisin B1 (FB1) are widely (co-) detected in food and
known for their hepatotoxicity in humans. Still, their combined toxicity needs to be …

Primary liver cancer includes hepatocellular carcinoma (HCC) and cholangiocarcinoma
(CCA). Incidence of liver cancer has been increasing in recent years, and the 5-year survival …

Alcohol-associated liver disease (ALD) is an intricate disease that results in a broad
spectrum of liver damage. The presentation of ALD can include simple steatosis …

Simple Summary Hepatocellular carcinoma is the most common primary liver malignancy in
the United States. Macrophages are immune cells that play a critical role in the promotion of …

Primary sclerosing cholangitis (PSC) is an idiopathic chronic immune-mediated cholestatic
liver disease characterized by fibro-inflammatory bile duct strictures, progressive …

The tumor microenvironment (TME) is a complex and dynamic ecosystem that includes a
variety of immune cells mutually interacting with tumor cells, structural/stromal cells, and …

Due to a combination of rapid disease progression and the lack of curative treatment
options, hepatocellular carcinoma (HCC) is one of the deadliest cancers worldwide …