Ameliorative and protective effects of ginger and its main constituents against natural, chemical and radiation-induced toxicities: A comprehensive review

MA Alsherbiny, WH Abd-Elsalam, E Taher… - Food and Chemical …, 2019 - Elsevier
Fatal unintentional poisoning is widespread upon human exposure to toxic agents such as
pesticides, heavy metals, environmental pollutants, bacterial and fungal toxins or even some …

Natural products as protective agents for male fertility

RVL Martins, AMS Silva, AP Duarte, S Socorro… - BioChem, 2021 - mdpi.com
The male reproductive system is highly susceptible to noxious influences, such as oxidative
stress, inflammation, drugs, and even diseases that can induce germ cell damage and …

Comparative chemical and biochemical analysis of extracts of Hibiscus sabdariffa

HA Sindi, LJ Marshall, MRA Morgan - Food chemistry, 2014 - Elsevier
Hibiscus sabdariffa extracts have attracted attention because of potentially useful bioactivity.
However, there have been no systematic studies of extraction efficiencies of H. sabdariffa …

Protective effect of curcumin in cisplatin-induced oxidative injury in rat testis: mitogen-activated protein kinase and nuclear factor-kappa B signaling pathways

YO Ilbey, E Ozbek, M Cekmen, A Simsek… - Human …, 2009 - academic.oup.com
BACKGROUND The aim of this study was to investigate the cellular/biochemical
mechanisms by which cisplatin (CIS) causes testicular toxicity. We evaluated the role of …

A 35-day gavage safety assessment of ginger in rats

X Rong, G Peng, T Suzuki, Q Yang, J Yamahara… - Regulatory Toxicology …, 2009 - Elsevier
Ginger (Zingiber officinale Roscoe, Zingiberacae) is one of the most commonly used spices
around the world and a traditional medicinal plant that has been widely used in Chinese …

Effects of resveratrol on methotrexate‐induced testicular damage in rats

E Yuluğ, S Türedi, A Alver, S Türedi… - The scientific world …, 2013 - Wiley Online Library
This study investigated the probable protective effects of resveratrol (RES), an antioxidant,
against methotrexate‐(MTX‐) induced testis damage. Twenty‐four male Sprague Dawley …

The antiapoptotic and antioxidant effects of eugenol against cisplatin‐induced testicular damage in the experimental model

FN Ekinci Akdemir, S Yildirim, FM Kandemir… - Andrologia, 2019 - Wiley Online Library
Testicular dysfunction or damage is among the critical side effects of chemotherapeutic
drugs like cisplatin. This study was mapped out to assess the possible therapeutic effect of …

[HTML][HTML] Antiapoptotic and antioxidant effects of β-carotene against methotrexate-induced testicular injury

N Vardi, H Parlakpinar, B Ates, A Cetin, A Otlu - Fertility and sterility, 2009 - Elsevier
OBJECTIVE: To investigate the effect of β-carotene against testicular injury induced by
methotrexate (MTX). DESIGN: Experimental study. SETTING: Animal and histology …

The antioxidant activity of vitamin C, DPPD and L-cysteine against cisplatin-induced testicular oxidative damage in rats

EA Ahmed, HM Omar, SMM Ragb, AY Nasser - Food and Chemical …, 2011 - Elsevier
Oxidative stress has been proven to be involved in cisplatin (CP)-induced toxicity. The
present study was designed to evaluate the antioxidant activity of Vit C, N, N′-diphenyl-p …

Selenium and lycopene attenuate cisplatin-induced testicular toxicity associated with oxidative stress in Wistar rats

EA Salem, NA Salem, AM Maarouf, EC Serefoglu… - Urology, 2012 - Elsevier
OBJECTIVE: To investigate the potential protective effects of selenium and lycopene, either
alone or in combination, for cisplatin-induced oxidative stress and testicular dysfunction in …