The phylum Actinobacteria harbors many important human pathogens and also provides
one of the richest sources of natural products, including numerous antibiotics and other …

Molecular typing has revolutionized epidemiological studies of infectious diseases,
including those of a mycobacterial etiology. With the advent of fingerprinting techniques …

Rapid and simple-to-use diagnostic methods for tuberculosis are urgently needed. Recent
development has unveiled the diagnostic power of the CRISPR system in the detection of …

TubercuList (http://tuberculist. epfl. ch/), the relational database that presents genome-
derived information about H37Rv, the paradigm strain of Mycobacterium tuberculosis, has …

Mycobacterium tuberculosis (Mtb) exposure drives antibody responses, but whether patients
with active tuberculosis elicit protective antibodies, and against which antigens, is still …

Extensively drug-resistant (XDR) tuberculosis (TB), which is resistant to both first-and
second-line antibiotics, is an escalating problem, particularly in the Russian Federation …

Pyrazinamide (PZA) is a frontline anti-tuberculosis drug that plays a crucial role in the
treatment of both drug susceptible and multidrug-resistant tuberculosis (MDR-TB) …

The publication of the complete genome sequence for Mycobacterium tuberculosis H37Rv
in 1998 has had a great impact on the research community. Nonetheless, it is suspected that …

Pyrazinamide (PZA) is a frontline anti-tuberculosis drug that plays a crucial role in the
treatment of both drug-susceptible and multidrug-resistant tuberculosis (MDR-TB). PZA is a …

Objectives Although clofazimine has been traditionally used to treat leprosy, there is recent
interest in using clofazimine for the treatment of MDR-TB and drug-susceptible TB. However …