White adipose tissue was believed to be just an energy-storage organ, but it is now
recognized to be an active participant in energy homoeostasis and physiological functions …

The rate of obesity is rising logarithmically, especially in those with severe obesity (body
mass index [BMI] 40 kg/m2). Cardiologists, endocrinologists, internists, family practitioners …

Background The bridge between food intake and weight is not fully understood. Recently,
the role of gut microbiota and bacterial lipopolysacharides (LPS) in weight has been noted …

Following the discovery of TNF-α and leptin as secretory products of adipocytes in the early
1990s, subsequent obesity research focused on the new functional role of adipose tissue, as …

The recent major increase in the global incidence of type 2 diabetes suggests that most
cases of this disease are caused by changes in environment and lifestyle. All major risk …

Depression and metabolic disorders, including overweight and obesity, appear tightly
interrelated. The prevalence of these conditions is concurrently growing worldwide, and both …

Pre-B cell colony-enhancing factor (PBEF), also known as visfatin, is a highly conserved, 52-
kDa protein found in living species from bacteria to humans. Originally a curiosity identified …

Obesity is characterised by an expansion of white adipose tissue mass that can lead to
adverse health effects, such as decreased longevity, diabetes mellitus, orthopaedic and …

Background There is an association between overweight status and life span in kenneled
dogs, but a similar association has not been reported for pet dogs. Objectives To examine …

Adipokines play a significant role in the pathogenesis of a low-grade inflammation
associated with obesity and metabolic syndrome, and in chronic inflammatory and …