Most chemotherapeutic agents are given by intravenous administration, although some
drugs are available orally. When given intravenously, these drugs cause few side-effects at …

OBJECTIVES: To describe the mechanisms of injury associated with DNA binding and DNA
non-binding vesicants. To review various procedures used in clinical practice to manage …

Introduction Extravasation is an iatrogenic injury that may produce soft tissue necrosis
requiring surgical reconstruction (Rose et al., 2008) and (Goon et al., 2006). 1, 2 Previous …

Methods Records from 102 consecutive CT contrast media extravasation injuries were
identified. Data acquired from a single institution included type and amount of contrast …

Extravasation injury occurs when fluid from an intravenous (IV) line leaks into the
surrounding tissue spaces. It has the potential to cause significant long standing aesthetic …

Doxorubicin (DXR) is a very potent drug with broad spectrum of biological activity, used to
treat a wide variety of human malignancies and many solid tumors. The Clinical efficacy of …

In the present study, we investigated a part of the mechanism responsible for the effects of
hot and cold compresses for extravasation of doxorubicin. We injected 20 μl of doxorubicin …

In our hospital, an adverse event reporting system was initiated that alerts the plastic surgery
department immediately after suspecting contrast media extravasation injury. This system is …