Once thought of as arising from “junk DNA,” non-coding RNAs (ncRNAs) have emerged as
key molecules in cellular processes and response to stress. From diseases such as cancer …

Radiotherapy is a cancer treatment that applies high doses of ionizing radiation to induce
cell death, mainly by triggering DNA double-strand breaks. The outcome of radiotherapy …

Background & Aims Tumor resistance to radiation is a challenge in the treatment of patients
with pancreatic cancer. Improving our understanding of the mechanisms of radioresistance …

BACKGROUND Papillary thyroid cancer (PTC) persistence or recurrence and the need for
long‐term surveillance can cause significant inconvenience and morbidity in patients …

Mammalian apurinic/apyrimidinic endonuclease 1 is a DNA repair enzyme involved in
genome stability and expression of genes involved in oxidative stress responses, tumor …

Glioblastoma multiforme (GBM) is the most aggressive brain cancer, and to date, no curative
treatment has been developed. In this study, we report that miR-211, a microRNA predicted …

Abstract Background MiR-221 and miR-222 (miR-221/222), upregulated in gliomas, can
regulate glioma cell cycle progression and apoptosis, respectively. However, the association …

BACKGROUND Accumulating evidence indicates that microRNAs play a pivotal role in the
development and progression of prostate cancer. The present study was aimed at clarifying …

Background Phosphatase and tensin homologue (PTEN), as a tumor suppressor, plays vital
roles in tumorigenesis and progression of prostate cancer. However, the mechanisms of …

Background: Chemoresistance is a main obstacle to effective esophageal cancer (EC)
therapy. We hypothesize that altered expression of microRNAs (miRNAs) play a role in EC …