The liposomal amphotericin B (AmB) formulation, AmBisome®, still represents the best
therapeutic option for cutaneous and visceral leishmaniasis. However, its clinical efficacy …

This review examined a collection of studies regarding the molecular properties of some
polyene antibiotic molecules as well as their properties in solution and in particular …

Antifungal drugs such as amphotericin B (AmB) interact with lipids and phospholipids
located on fungal cell membranes to disrupt them and create pores, leading to cell apoptosis …

Natamycin is a polyene macrolide, widely employed to treat fungal keratitis and other yeast
infections as well as to protect food products against fungal molds. In contrast to other …

Amphotericin B (AmB) is regarded as a first-line therapy against life-threatening invasive
fungal infections. Due to its poor oral bioavailability, AmB is restricted to intravenous …

Biomimetic synthesis of nanoparticles offers a convenient and bio friendly approach to
fabricate complex structures with sub-nanometer precision from simple precursor …

Safer and efficacious Amphotericin B (AmB) nanoformulations can be designed by
augmenting AmB in the monomeric or super-aggregated state, and restricting the …

Amphotericin B is a popular antifungal antibiotic, a gold standard in treatment of systemic
mycotic infections, due to its high effectiveness. On the other hand, applicability of the drug is …

In the present study, new polymer microspheres of amphotericin B (AmB) were prepared by
a spray drying technique using cyclodextrin polymers (Poly-CD) to improve the solubility and …

Amphotericin B is a lifesaving polyene antibiotic used in the treatment of systemic mycoses.
Unfortunately, the pharmacological applicability of this drug is limited because of its severe …