Tryptase as a polyfunctional component of mast cells
D Atiakshin, I Buchwalow, V Samoilova… - Histochemistry and cell …, 2018 - Springer
Mast cells are haematopoietic cells that arise from pluripotent precursors of the bone
marrow. They play immunomodulatory roles in both health and disease. When appropriately …
marrow. They play immunomodulatory roles in both health and disease. When appropriately …
Anorexia nervosa: Gut microbiota-immune-brain interactions
R Roubalová, P Procházková, H Papežová, K Smitka… - Clinical Nutrition, 2020 - Elsevier
Anorexia nervosa is a psychiatric disorder defined by an extremely low body weight, a
devastating fear of weight gain, and body image disturbance, however the etiopathogenesis …
devastating fear of weight gain, and body image disturbance, however the etiopathogenesis …
Quercetin is more effective than cromolyn in blocking human mast cell cytokine release and inhibits contact dermatitis and photosensitivity in humans
Mast cells are immune cells critical in the pathogenesis of allergic, but also inflammatory and
autoimmune diseases through release of many pro-inflammatory cytokines such as IL-8 and …
autoimmune diseases through release of many pro-inflammatory cytokines such as IL-8 and …
Induction of IL-33 expression and activity in central nervous system glia
IL-33 is a novel member of the IL-1 cytokine family and a potent inducer of type 2 immunity,
as mast cells and Th2 CD4+ T cells respond to IL-33 with the induction of type 2 cytokines …
as mast cells and Th2 CD4+ T cells respond to IL-33 with the induction of type 2 cytokines …
Brain mast cells link the immune system to anxiety-like behavior
KM Nautiyal, AC Ribeiro, DW Pfaff… - Proceedings of the …, 2008 - National Acad Sciences
Mast cells are resident in the brain and contain numerous mediators, including
neurotransmitters, cytokines, and chemokines, that are released in response to a variety of …
neurotransmitters, cytokines, and chemokines, that are released in response to a variety of …
The skin as a mirror of the soul: exploring the possible roles of serotonin
K Nordlind, EC Azmitia… - Experimental dermatology, 2008 - Wiley Online Library
Serotonin (5‐hydroxytryptamine; 5‐HT) is an important mediator of bidirectional interactions
between the neuroendocrine system and the skin. The rate of synthesis of 5‐HT from l …
between the neuroendocrine system and the skin. The rate of synthesis of 5‐HT from l …
A focus on mast cells and pain
Mast cells (MCs) are immunocytes with secretory functions that act locally in peripheral
tissues to modulate local hemodynamics, nociceptor activation and pain. They are also able …
tissues to modulate local hemodynamics, nociceptor activation and pain. They are also able …
P2 receptor-mediated signaling in mast cell biology
E Bulanova, S Bulfone-Paus - Purinergic signalling, 2010 - Springer
Mast cells are widely recognized as effector cells of allergic inflammatory reactions. They
contribute to the pathogenesis of different chronic inflammatory diseases, wound healing …
contribute to the pathogenesis of different chronic inflammatory diseases, wound healing …
Mast cells: an expanding pathophysiological role from allergy to other disorders
The mast cells are multi-effector cells with wide distribution in the different body parts and
traditionally their role has been well-defined in the development of IgE-mediated …
traditionally their role has been well-defined in the development of IgE-mediated …
The mast cell degranulator compound 48/80 directly activates neurons
M Schemann, EM Kugler, S Buhner, C Eastwood… - PLoS …, 2012 - journals.plos.org
Background Compound 48/80 is widely used in animal and tissue models as a “selective”
mast cell activator. With this study we demonstrate that compound 48/80 also directly …
mast cell activator. With this study we demonstrate that compound 48/80 also directly …