The fight against cancer by microgravity: the multicellular spheroid as a metastasis model
Cancer is a disease exhibiting uncontrollable cell growth and spreading to other parts of the
organism. It is a heavy, worldwide burden for mankind with high morbidity and mortality …
organism. It is a heavy, worldwide burden for mankind with high morbidity and mortality …
Role of apoptosis in wound healing and apoptosis alterations in microgravity
S Riwaldt, TJ Corydon, D Pantalone… - … in bioengineering and …, 2021 - frontiersin.org
Functioning as the outermost self-renewing protective layer of the human organism, skin
protects against a multitude of harmful biological and physical stimuli. Consisting of …
protects against a multitude of harmful biological and physical stimuli. Consisting of …
Current knowledge about the impact of microgravity on gene regulation
Microgravity (µ g) has a massive impact on the health of space explorers. Microgravity
changes the proliferation, differentiation, and growth of cells. As crewed spaceflights into …
changes the proliferation, differentiation, and growth of cells. As crewed spaceflights into …
[HTML][HTML] The impact of spaceflight and simulated microgravity on cell adhesion
Microgravity induces a number of significant physiological changes in the cardiovascular,
nervous, immune systems, as well as the bone tissue of astronauts. Changes in cell …
nervous, immune systems, as well as the bone tissue of astronauts. Changes in cell …
Morphological and molecular changes in juvenile normal human fibroblasts exposed to simulated microgravity
The literature suggests morphological alterations and molecular biological changes within
the cellular milieu of human cells, exposed to microgravity (µ g), as many cell types …
the cellular milieu of human cells, exposed to microgravity (µ g), as many cell types …
Biological and mechanical characterization of the random positioning machine (rpm) for microgravity simulations
M Calvaruso, C Militello, L Minafra, V La Regina… - Life, 2021 - mdpi.com
The rapid improvement of space technologies is leading to the continuous increase of space
missions that will soon bring humans back to the Moon and, in the coming future, toward …
missions that will soon bring humans back to the Moon and, in the coming future, toward …
Effects of the Escherichia coli Bacterial Toxin Cytotoxic Necrotizing Factor 1 on Different Human and Animal Cells: A Systematic Review
F Carlini, Z Maroccia, C Fiorentini… - International journal of …, 2021 - mdpi.com
Cytotoxic necrotizing factor 1 (CNF1) is a bacterial virulence factor, the target of which is
represented by Rho GTPases, small proteins involved in a huge number of crucial cellular …
represented by Rho GTPases, small proteins involved in a huge number of crucial cellular …
Fighting thyroid cancer with microgravity research
Microgravity in space or simulated by special ground-based devices provides an unusual
but unique environment to study and influence tumour cell processes. By investigating …
but unique environment to study and influence tumour cell processes. By investigating …
Apoptosis induction and alteration of cell adherence in human lung cancer cells under simulated microgravity
C Dietz, M Infanger, A Romswinkel, F Strube… - International journal of …, 2019 - mdpi.com
Background: Lung cancer cells are known to change proliferation and migration under
simulated microgravity. In this study, we sought to evaluate cell adherence, apoptosis …
simulated microgravity. In this study, we sought to evaluate cell adherence, apoptosis …
Activation of Focal Adhesion Kinase Restores Simulated Microgravity-Induced Inhibition of Osteoblast Differentiation via Wnt/Β-Catenin Pathway
C Fan, Z Wu, DML Cooper, A Magnus… - International Journal of …, 2022 - mdpi.com
Simulated microgravity (SMG) inhibits osteoblast differentiation (OBD) and induces bone
loss via the inhibition of the Wnt/β-catenin pathway. However, the mechanism by which SMG …
loss via the inhibition of the Wnt/β-catenin pathway. However, the mechanism by which SMG …