This review aims to survey the current state of mechanotransduction in vascular smooth
muscle cells (VSMCs) and endothelial cells (ECs), including their sensing of mechanical …

Hypertension is a major risk factor for many common chronic diseases, such as heart failure,
myocardial infarction, stroke, vascular dementia, and chronic kidney disease …

Aims Embryonic vascular smooth muscle cells (vSMCs) have a synthetic phenotype; in
adults, they commit to the mature contractile phenotype. Research shows that human …

Spermatogenesis, the complex process of male germ cell proliferation, differentiation, and
maturation, is the basis of male fertility. In the seminiferous tubules of the testes …

Background Maintenance of the structure and mechanical properties of the thoracic aorta
contributes to aortic function and is dependent on the composition of the extracellular matrix …

A group of proteases, the matrix metalloproteinases (MMPs) are well known for their
capacity to degrade extracellular matrix (ECM) proteins. Particularly MMP-2 and MMP-9 …

Tissue engineering is an alternative method for preparing small‐caliber (< 6 mm) vascular
grafts. Dynamic mechanical conditioning is being researched as a method to improve …

Arterial wall tissues are sensitive to their mechanical surroundings and remodel their
structure and mechanical properties when subjected to mechanical stimuli such as …

Force-sensing biophysical cues in microenvironment, including extracellular matrix
performances, stretch-mediated mechanics, shear stress and flow-induced hemodynamics …

Advanced techniques of reconstructive urology are gradually reaching their limits in terms of
their ability to restore urinary tract function and patients' quality of life. A tissue engineering …