Technological developments in lncRNA biology
S Jathar, V Kumar, J Srivastava, V Tripathi - Long Non Coding RNA …, 2017 - Springer
It is estimated that more than 90% of the mammalian genome is transcribed as non-coding
RNAs. Recent evidences have established that these non-coding transcripts are not junk or …
RNAs. Recent evidences have established that these non-coding transcripts are not junk or …
Long non-coding RNAs: a novel paradigm for toxicology
JL Dempsey, JY Cui - Toxicological Sciences, 2017 - academic.oup.com
Long non-coding RNAs (lncRNAs) are over 200 nucleotides in length and are transcribed
from the mammalian genome in a tissue-specific and developmentally regulated pattern …
from the mammalian genome in a tissue-specific and developmentally regulated pattern …
Structural, super-resolution microscopy analysis of paraspeckle nuclear body organization
Paraspeckles are nuclear bodies built on the long noncoding RNA Neat1, which regulates a
variety of physiological processes including cancer progression and corpus luteum …
variety of physiological processes including cancer progression and corpus luteum …
The role of long non-coding RNAs in rheumatic diseases
Long non-coding RNAs (lncRNAs) have emerged as key epigenetic regulators that govern
gene expression and influence multiple biological processes. Accumulating evidence …
gene expression and influence multiple biological processes. Accumulating evidence …
Long ncRNA A-ROD activates its target gene DKK1 at its release from chromatin
Long ncRNAs are often enriched in the nucleus and at chromatin, but whether their
dissociation from chromatin is important for their role in transcription regulation is unclear …
dissociation from chromatin is important for their role in transcription regulation is unclear …
Probing long non-coding RNA-protein interactions
Non-coding RNA sequences outnumber the protein-coding genes in the human genome,
however our knowledge of their functions is still limited. RNA-binding proteins follow the …
however our knowledge of their functions is still limited. RNA-binding proteins follow the …
[HTML][HTML] Emerging roles for long noncoding RNAs in B-cell development and malignancy
M Winkle, JL Kluiver, A Diepstra… - Critical reviews in …, 2017 - Elsevier
Long noncoding (lnc) RNAs have emerged as essential mediators of cellular biology,
differentiation and malignant transformation. LncRNAs have a broad range of possible …
differentiation and malignant transformation. LncRNAs have a broad range of possible …
Proximity-dependent recruitment of Polycomb repressive complexes by the lncRNA Airn
AK Braceros, MD Schertzer, A Omer, JB Trotman… - Cell reports, 2023 - cell.com
During mouse embryogenesis, expression of the long non-coding RNA (lncRNA) Airn leads
to gene repression and recruitment of Polycomb repressive complexes (PRCs) to varying …
to gene repression and recruitment of Polycomb repressive complexes (PRCs) to varying …
Elements at the 5′ end of Xist harbor SPEN-independent transcriptional antiterminator activity
JB Trotman, DM Lee, RE Cherney, SO Kim… - Nucleic Acids …, 2020 - academic.oup.com
Abstract The Xist lncRNA requires Repeat A, a conserved RNA element located in its 5′
end, to induce gene silencing during X-chromosome inactivation. Intriguingly, Repeat A is …
end, to induce gene silencing during X-chromosome inactivation. Intriguingly, Repeat A is …
Methods to study long noncoding RNA biology in cancer
ML Luo - The Long and Short Non-coding RNAs in Cancer …, 2016 - Springer
Thousands of long noncoding RNAs (lncRNAs) have been discovered in recent years. The
functions of lncRNAs range broadly from regulating chromatin structure and gene …
functions of lncRNAs range broadly from regulating chromatin structure and gene …