With the emerging advances in utilizing nanocarriers for biomedical applications, a
molecular-level understanding of the in vivo fate of nanocarriers is necessary. After …

Nanomaterials offer promising solutions as drug delivery systems and imaging agents in
response to the demand for better therapeutics and diagnostics. However, the limited …

This Review aims to provide a systematic analysis of the literature regarding ongoing
debates in protein corona research. Our goal is to portray the current understanding of two …

For successful translation of targeting nanomedicines from bench to bedside, it is vital to
address their most common drawbacks namely rapid clearance and off-target accumulation …

Owing to the inherent shortcomings of traditional therapeutic drugs in terms of inadequate
therapeutic efficacy and toxicity in clinical treatment, nanomedicine designs have received …

High quantum yield quantum dots (QDs) with the emission in the sub-second near infrared
window (NIR-IIb, 1500–1700 nm) can afford higher resolution, a deeper penetration depth …

Highlights•The current status of nanomedicines and their clinical translation is summarized.•
Challenges to the clinical translation of nanomedicines are summarized.•Strategies and …

The failure of immune responses to vaccines and dysfunctional immune responses to viral
infection, tumor development, or neoantigens lead to chronic viral infection, tumor …

Conspectus With a plethora of advances in nanotechnology and biotechnology, the
development of natural particle-based drug delivery vectors is a rapidly emerging field; …

Plant virus nanoparticles (PVNPs) have inherent immune stimulatory ability, and have been
investigated as immune adjuvants to stimulate an anti-tumor immune response. The …