Membrane proteins play a most important part in metabolism, signaling, cell motility,
transport, development, and many other biochemical and biophysical processes which …

Membrane proteins have long presented a challenge to biochemical and functional studies.
In the absence of a bilayer environment, individual proteins and critical macromolecular …

G-protein-coupled receptors (GPCRs) signal primarily through G proteins or arrestins.
Arrestin binding to GPCRs blocks G protein interaction and redirects signalling to numerous …

The light sensor of vertebrate scotopic (low-light) vision, rhodopsin, is a G-protein-coupled
receptor comprising a polypeptide chain with bound chromophore, 11-cis-retinal, that …

Most evidence indicates that, as for family CG protein–coupled receptors (GPCRs), family A
GPCRs form homo-and heteromers. Homodimers seem to be a predominant species, with …

Membrane proteins are involved in numerous vital biological processes, including transport,
signal transduction and the enzymes in a variety of metabolic pathways. Integral membrane …

One of the recently emerging topics in biotechnology is natural receptors including G protein-
coupled receptors, ligand-gated ion channels, enzyme-linked receptors, and intracellular …

Nanodiscs are soluble nanoscale phospholipid bilayers which can self-assemble integral
membrane proteins for biophysical, enzymatic or structural investigations. This means for …

Self-assembled phospholipid bilayer Nanodiscs have become an important and versatile
tool among model membrane systems to functionally reconstitute membrane proteins …

Suitable membrane mimetics are crucial to the performance of structural and functional
studies of membrane proteins. Phospholipid nanodiscs (formed when a membrane scaffold …