Murine Double Minute Clone 2, located at 12q15, is an oncogene that codes for an
oncoprotein of which the association with p53 was discovered 30 years ago. The most …

Dedifferentiated liposarcoma (DDL) is defined as the transition from well-differentiated
liposarcoma (WDL)/atypical lipomatous tumor (ALT) to non-lipogenic sarcoma, which arises …

The genetic, biologic, and clinical heterogeneity of sarcomas poses a challenge for the
identification of therapeutic targets, clinical research, and advancing patient care. Because …

Dedifferentiated liposarcoma (DDLPS) is the most frequent high-grade soft tissue sarcoma
subtype. It is characterized by a component of undifferentiated tumor cells coexisting with a …

Soft tissue sarcoma is a broad family of mesenchymal malignancies exhibiting remarkable
histological diversity. We portray the proteomic landscape of 272 soft tissue sarcomas …

Liposarcoma, the most common soft tissue sarcoma, is a group of fat cell mesenchymal
tumors with different histological subtypes. The dysregulation of long non-coding RNAs …

Adipocytic tumours are among the most common mesenchymal neoplasms, and constitute a
clinically, biologically and pathologically diverse group. Their wide histological spectrum …

Well-differentiated liposarcoma (WDLPS) is the most frequent subtype of liposarcoma and
may transform into dedifferentiated liposarcoma (DDLPS) which is a more aggressive …

Background Sarcomas are diverse neoplasms with highly variable histological appearances
in which diagnosis is often challenging and management options for metastatic …

Simple Summary Liposarcoma is the most widespread soft-tissue sarcoma in adults. This
review summarizes the molecular genetics and epigenetics of the main liposarcoma …