How membrane-active peptides get into lipid membranes

MA Sani, F Separovic - Accounts of chemical research, 2016 - ACS Publications
Conspectus The structure–function relationship for a family of antimicrobial peptides (AMPs)
from the skin of Australian tree frogs is discussed and compared with that of peptide toxins …

The chemistry and biological activities of peptides from amphibian skin secretions

X Xu, R Lai - Chemical reviews, 2015 - ACS Publications
Amphibian skin is directly exposed to different environments. Amphibians interact with
environmental factors including microorganisms, parasites, predators, and physical factors …

Amphipathic, α‐helical antimicrobial peptides

A Tossi, L Sandri, A Giangaspero - Peptide Science, 2000 - Wiley Online Library
Gene‐encoded antimicrobial peptides are an important component of host defense in
animals ranging from insects to mammals. They do not target specific molecular receptors …

The antibiotic and anticancer active aurein peptides from the Australian Bell Frogs Litoria aurea and Litoria raniformis The solution structure of aurein 1.2

T Rozek, KL Wegener, JH Bowie… - European Journal of …, 2000 - Wiley Online Library
Seventeen aurein peptides are present in the secretion from the granular dorsal glands of
the Green and Golden Bell Frog Litoria aurea, and 16 from the corresponding secretion of …

The diversity and evolution of anuran skin peptides

E König, ORP Bininda-Emonds, C Shaw - Peptides, 2015 - Elsevier
Amphibians exhibit various, characteristic adaptations related to their “incomplete” shift from
the aquatic to the terrestrial habitat. In particular, the integument was subject to a number of …

Discovery and characterization of a peptide that enhances endosomal escape of delivered proteins in vitro and in vivo

M Li, Y Tao, Y Shu, JR LaRochelle… - Journal of the …, 2015 - ACS Publications
The inefficient delivery of proteins into mammalian cells remains a major barrier to realizing
the therapeutic potential of many proteins. We and others have previously shown that …

Direct visualization of membrane leakage induced by the antibiotic peptides: maculatin, citropin, and aurein

EE Ambroggio, F Separovic, JH Bowie, GD Fidelio… - Biophysical journal, 2005 - cell.com
Membrane lysis caused by antibiotic peptides is often rationalized by means of two different
models: the so-called carpet model and the pore-forming model. We report here on the lytic …

Host-defence peptides of Australian anurans: structure, mechanism of action and evolutionary significance

MA Apponyi, TL Pukala, CS Brinkworth, VM Maselli… - Peptides, 2004 - Elsevier
Host-defence peptides secreted from the skin glands of Australian frogs and toads, are, with
a few notable exceptions, different from those produced by anurans elsewhere. This review …

Host-defence peptides from the glandular secretions of amphibians: structure and activity

TL Pukala, JH Bowie, VM Maselli, IF Musgrave… - Natural product …, 2006 - pubs.rsc.org
Covering: up to the end of 2005 This review covers the literature on the subject of
biologically active peptides from the glands of amphibians. These include neuropeptides …

Potential application of antimicrobial peptides in the treatment of bacterial biofilm infections

N Strempel, J Strehmel… - Current pharmaceutical …, 2015 - ingentaconnect.com
The increasing prevalence of persistent biofilm infections, such as wound infections, chronic
lung infections or medical device-related infections, which usually tolerate conventional …